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PubMed code 24189186

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM82088
PNG
(CAS_15574-96-6 | NSC_27400 | PIZOTIFEN)
Show SMILES CN1CCC(CC1)=C1c2ccsc2CCc2ccccc12
Show InChI InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
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Article
PubMed
2.40n/an/an/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Binding affinity to dopamine D2 receptor (unknown origin)


Bioorg Med Chem 21: 7841-52 (2013)


Article DOI: 10.1016/j.bmc.2013.10.010
BindingDB Entry DOI: 10.7270/Q2FN17N0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50444039
PNG
(CHEMBL3092759)
Show SMILES NC(=N)NC(=O)c1ccc-2c(c1)C(O)c1ccccc-21
Show InChI InChI=1S/C15H13N3O2/c16-15(17)18-14(20)8-5-6-10-9-3-1-2-4-11(9)13(19)12(10)7-8/h1-7,13,19H,(H4,16,17,18,20)
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PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Binding affinity to dopamine D2 receptor (unknown origin)


Bioorg Med Chem 21: 7841-52 (2013)


Article DOI: 10.1016/j.bmc.2013.10.010
BindingDB Entry DOI: 10.7270/Q2FN17N0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50444040
PNG
(CHEMBL3092753)
Show SMILES NC(=N)NC(=O)c1ccc-2c(Cc3ccccc-23)c1
Show InChI InChI=1S/C15H13N3O/c16-15(17)18-14(19)10-5-6-13-11(8-10)7-9-3-1-2-4-12(9)13/h1-6,8H,7H2,(H4,16,17,18,19)
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
1.40E+3n/an/an/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Binding affinity to dopamine D2 receptor (unknown origin)


Bioorg Med Chem 21: 7841-52 (2013)


Article DOI: 10.1016/j.bmc.2013.10.010
BindingDB Entry DOI: 10.7270/Q2FN17N0
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%