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PubMed code 24266709

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Rattus norvegicus)
BDBM50445387
PNG
(CHEMBL3105479)
Show SMILES CCc1cc(cc(C)c1CCC(O)=O)-c1noc(n1)-c1sc(C)c2[C@H]3[C@@H](Cc12)C3(C)C
Show InChI InChI=1S/C25H28N2O3S/c1-6-14-10-15(9-12(2)16(14)7-8-19(28)29)23-26-24(30-27-23)22-17-11-18-21(25(18,4)5)20(17)13(3)31-22/h9-10,18,21H,6-8,11H2,1-5H3,(H,28,29)/t18-,21-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.40n/an/an/an/a



Actelion Pharmaceuticals Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at rat S1P1 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding preincubated for 30 mins followed by [...


J Med Chem 56: 9737-55 (2014)


Article DOI: 10.1021/jm4014373
BindingDB Entry DOI: 10.7270/Q2PN9731
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%