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Found 24 Enz. Inhib. hit(s) with all data for entry = 50043742
TargetG protein-coupled receptor 119(Macaca fascicularis)
Amgen

Curated by ChEMBL
LigandPNGBDBM50445481(CHEMBL3104879)
Affinity DataEC50:  73nMAssay Description:Agonist activity at cynomolgus monkey GPR119 assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50445481(CHEMBL3104879)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at mouse GPR119 assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445483(CHEMBL3104861)
Affinity DataEC50:  357nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445481(CHEMBL3104879)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445484(CHEMBL3104880)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445485(CHEMBL3104881)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445486(CHEMBL3104882)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445487(CHEMBL3104883)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445488(CHEMBL3104884)
Affinity DataEC50:  238nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445489(CHEMBL3104885)
Affinity DataEC50:  382nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445490(CHEMBL3104886)
Affinity DataEC50:  224nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445491(CHEMBL3104896)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445492(CHEMBL3104895)
Affinity DataEC50:  299nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445493(CHEMBL3104894)
Affinity DataEC50:  69nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445494(CHEMBL3104893)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445495(CHEMBL3104892)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445496(CHEMBL3104891)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445497(CHEMBL3104890)
Affinity DataEC50:  121nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445498(CHEMBL3104889)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445499(CHEMBL3104888)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445500(CHEMBL3104887)
Affinity DataEC50:  45nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50343449(CHEMBL1775171 | isopropyl 4-(1-(4-(methylsulfonyl)...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50445481(CHEMBL3104879)
Affinity DataEC50:  2.05E+3nMAssay Description:Agonist activity at rat GPR119 assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50445482(CHEMBL3104862)
Affinity DataEC50:  493nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed