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Found 30 Enz. Inhib. hit(s) with all data for entry = 50044332
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  23nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013258(CHEMBL3262641)
Affinity DataIC50:  87nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013264(CHEMBL3262645)
Affinity DataIC50:  200nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013266(CHEMBL3262647)
Affinity DataIC50:  270nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013246(CHEMBL3262632)
Affinity DataIC50:  270nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013263(CHEMBL3262644)
Affinity DataIC50:  270nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013256(CHEMBL3262639)
Affinity DataIC50:  300nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013257(CHEMBL3262640)
Affinity DataIC50:  350nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013265(CHEMBL3262646)
Affinity DataIC50:  380nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013262(CHEMBL3262643)
Affinity DataIC50:  420nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013259(CHEMBL3262642)
Affinity DataIC50:  440nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013244(CHEMBL3262630)
Affinity DataIC50:  520nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013253(CHEMBL3262636)
Affinity DataIC50:  550nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013275(CHEMBL3262654)
Affinity DataIC50:  650nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013176(CHEMBL3262627)
Affinity DataIC50:  690nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013268(CHEMBL3262648)
Affinity DataIC50:  740nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013247(CHEMBL3262633)
Affinity DataIC50:  790nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013274(CHEMBL3262653)
Affinity DataIC50:  890nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013272(CHEMBL3262651)
Affinity DataIC50:  910nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013270(CHEMBL3262649)
Affinity DataIC50:  960nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013254(CHEMBL3262637)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013180(CHEMBL3259848)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013255(CHEMBL3262638)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013273(CHEMBL3262652)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013178(CHEMBL3262629)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013245(CHEMBL3262631)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013271(CHEMBL3262650)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013177(CHEMBL3262628)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013249(CHEMBL3262634)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013250(CHEMBL3262635)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed