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PubMed code 24792774

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50399540
PNG
(FORETINIB)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
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n/an/a 0.400n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin)


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016069
PNG
(CHEMBL3260966)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4c(I)ccn(-c5ccc(F)cc5)c4=O)cc3F)c2cc1OC
Show InChI InChI=1S/C29H20F2IN3O5/c1-38-25-14-19-22(15-26(25)39-2)33-11-9-23(19)40-24-8-5-17(13-20(24)31)34-28(36)27-21(32)10-12-35(29(27)37)18-6-3-16(30)4-7-18/h3-15H,1-2H3,(H,34,36)
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n/an/a 0.700n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016070
PNG
(CHEMBL3260967)
Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(F)c1
Show InChI InChI=1S/C31H25F2N3O6/c1-4-41-26-12-14-36(20-8-5-18(32)6-9-20)31(38)29(26)30(37)35-19-7-10-25(22(33)15-19)42-24-11-13-34-23-17-28(40-3)27(39-2)16-21(23)24/h5-17H,4H2,1-3H3,(H,35,37)
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n/an/a 0.900n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016071
PNG
(CHEMBL3260968)
Show SMILES COc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(F)c1
Show InChI InChI=1S/C30H23F2N3O6/c1-38-25-11-13-35(19-7-4-17(31)5-8-19)30(37)28(25)29(36)34-18-6-9-24(21(32)14-18)41-23-10-12-33-22-16-27(40-3)26(39-2)15-20(22)23/h4-16H,1-3H3,(H,34,36)
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n/an/a 1.70n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50271981
PNG
(1-(3-fluoro-4-(3-(pyridin-3-yl)-1H-pyrrolo[2,3-b]p...)
Show SMILES Fc1ccc(CC(=O)NC(=O)Nc2ccc(Oc3ccnc4[nH]cc(-c5cccnc5)c34)c(F)c2)cc1
Show InChI InChI=1S/C27H19F2N5O3/c28-18-5-3-16(4-6-18)12-24(35)34-27(36)33-19-7-8-22(21(29)13-19)37-23-9-11-31-26-25(23)20(15-32-26)17-2-1-10-30-14-17/h1-11,13-15H,12H2,(H,31,32)(H2,33,34,35,36)
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n/an/a 2n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin)


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM28031
PNG
(BMS-777607 | N-{4-[(2-amino-3-chloropyridin-4-yl)o...)
Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc(N)c2Cl)c(F)c1
Show InChI InChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)
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n/an/a 3.70n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016077
PNG
(CHEMBL3260962)
Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4[nH]ccc34)c(F)c2)c1=O
Show InChI InChI=1S/C24H15F2N5O3/c25-14-3-6-16(7-4-14)31-11-1-2-18(24(31)33)22(32)30-15-5-8-20(19(26)12-15)34-23-17-9-10-27-21(17)28-13-29-23/h1-13H,(H,30,32)(H,27,28,29)
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n/an/a 20n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015966
PNG
(CHEMBL3260969)
Show SMILES CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=S)N4CCN(C4=O)c4ccc(F)cc4)cc3F)c2s1
Show InChI InChI=1S/C28H22F2N6O2S2/c1-2-34-15-22(32-16-34)25-14-21-26(40-25)24(9-10-31-21)38-23-8-5-18(13-20(23)30)33-27(39)36-12-11-35(28(36)37)19-6-3-17(29)4-7-19/h3-10,13-16H,2,11-12H2,1H3,(H,33,39)
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n/an/a 27n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin)


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016078
PNG
(CHEMBL3260964)
Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc(N)n2)c(F)c1
Show InChI InChI=1S/C24H19F2N5O4/c1-2-34-19-10-12-31(16-6-3-14(25)4-7-16)23(33)21(19)22(32)29-15-5-8-18(17(26)13-15)35-20-9-11-28-24(27)30-20/h3-13H,2H2,1H3,(H,29,32)(H2,27,28,30)
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n/an/a 27n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM24498
PNG
(3-(3-fluoro-4-{[2-(1-methyl-1H-imidazol-4-yl)thien...)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C26H20FN5O2S2/c1-32-14-20(29-15-32)23-13-19-25(36-23)22(9-10-28-19)34-21-8-7-17(12-18(21)27)30-26(35)31-24(33)11-16-5-3-2-4-6-16/h2-10,12-15H,11H2,1H3,(H2,30,31,33,35)
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n/an/a 29n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin)


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016076
PNG
(CHEMBL3091589)
Show SMILES Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)n1
Show InChI InChI=1S/C22H15F2N5O3/c23-13-3-6-15(7-4-13)29-11-1-2-16(21(29)31)20(30)27-14-5-8-18(17(24)12-14)32-19-9-10-26-22(25)28-19/h1-12H,(H,27,30)(H2,25,26,28)
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n/an/a 39n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015999
PNG
(CHEMBL3260965)
Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ncnc3[nH]ccc23)c(F)c1
Show InChI InChI=1S/C26H19F2N5O4/c1-2-36-21-10-12-33(17-6-3-15(27)4-7-17)26(35)22(21)24(34)32-16-5-8-20(19(28)13-16)37-25-18-9-11-29-23(18)30-14-31-25/h3-14H,2H2,1H3,(H,32,34)(H,29,30,31)
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n/an/a 50n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015964
PNG
(CHEMBL3260953)
Show SMILES Nc1nccc(Oc2ccc(NC(=O)C3CCCN(c4ccc(F)cc4)S3(=O)=O)cc2F)c1Cl
Show InChI InChI=1S/C22H19ClF2N4O4S/c23-20-18(9-10-27-21(20)26)33-17-8-5-14(12-16(17)25)28-22(30)19-2-1-11-29(34(19,31)32)15-6-3-13(24)4-7-15/h3-10,12,19H,1-2,11H2,(H2,26,27)(H,28,30)
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n/an/a 70n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM24485
PNG
(3-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2cc1OC
Show InChI InChI=1S/C26H22FN3O4S/c1-32-23-14-18-20(15-24(23)33-2)28-11-10-21(18)34-22-9-8-17(13-19(22)27)29-26(35)30-25(31)12-16-6-4-3-5-7-16/h3-11,13-15H,12H2,1-2H3,(H2,29,30,31,35)
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n/an/a 80n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by liquid scintillation counting analysis in presence of [ga...


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016075
PNG
(CHEMBL3260961)
Show SMILES Nc1nccc(Oc2ccc(NC(=O)C3(Cl)CCCN(C3=O)c3ccc(F)cc3)cc2F)c1Cl
Show InChI InChI=1S/C23H18Cl2F2N4O3/c24-19-18(8-10-29-20(19)28)34-17-7-4-14(12-16(17)27)30-21(32)23(25)9-1-11-31(22(23)33)15-5-2-13(26)3-6-15/h2-8,10,12H,1,9,11H2,(H2,28,29)(H,30,32)
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n/an/a 81n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015965
PNG
(CHEMBL3260954)
Show SMILES Nc1nccc(Oc2ccc(NS(=O)(=O)CC(=O)Nc3ccccc3)cc2F)c1Cl
Show InChI InChI=1S/C19H16ClFN4O4S/c20-18-16(8-9-23-19(18)22)29-15-7-6-13(10-14(15)21)25-30(27,28)11-17(26)24-12-4-2-1-3-5-12/h1-10,25H,11H2,(H2,22,23)(H,24,26)
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n/an/a 101n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015963
PNG
(CHEMBL3260952)
Show SMILES Cc1ccc(cc1)N1CCCC(C(=O)Nc2ccc(Oc3ccnc(N)c3Cl)c(F)c2)S1(=O)=O
Show InChI InChI=1S/C23H22ClFN4O4S/c1-14-4-7-16(8-5-14)29-12-2-3-20(34(29,31)32)23(30)28-15-6-9-18(17(25)13-15)33-19-10-11-27-22(26)21(19)24/h4-11,13,20H,2-3,12H2,1H3,(H2,26,27)(H,28,30)
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n/an/a 166n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015998
PNG
(CHEMBL3260951)
Show SMILES Nc1nccc(Oc2ccc(NC(=O)C3CCCN(c4ccccc4)S3(=O)=O)cc2F)c1Cl
Show InChI InChI=1S/C22H20ClFN4O4S/c23-20-18(10-11-26-21(20)25)32-17-9-8-14(13-16(17)24)27-22(29)19-7-4-12-28(33(19,30)31)15-5-2-1-3-6-15/h1-3,5-6,8-11,13,19H,4,7,12H2,(H2,25,26)(H,27,29)
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n/an/a 169n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015967
PNG
(CHEMBL3260948)
Show SMILES Nc1nccc(Oc2ccc(NC(=O)CS(=O)(=O)Nc3ccccc3)cc2F)c1Cl
Show InChI InChI=1S/C19H16ClFN4O4S/c20-18-16(8-9-23-19(18)22)29-15-7-6-13(10-14(15)21)24-17(26)11-30(27,28)25-12-4-2-1-3-5-12/h1-10,25H,11H2,(H2,22,23)(H,24,26)
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n/an/a 291n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015988
PNG
(CHEMBL3260950)
Show SMILES Nc1nccc(Oc2ccc(NC(=O)CS(=O)(=O)Nc3ccc(F)cc3)cc2F)c1Cl
Show InChI InChI=1S/C19H15ClF2N4O4S/c20-18-16(7-8-24-19(18)23)30-15-6-5-13(9-14(15)22)25-17(27)10-31(28,29)26-12-3-1-11(21)2-4-12/h1-9,26H,10H2,(H2,23,24)(H,25,27)
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n/an/a 373n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016074
PNG
(CHEMBL3260960)
Show SMILES Nc1nccc(Oc2ccc(NC(=O)C3CCCN(C3=O)c3ccc(F)cc3)cc2F)c1Cl
Show InChI InChI=1S/C23H19ClF2N4O3/c24-20-19(9-10-28-21(20)27)33-18-8-5-14(12-17(18)26)29-22(31)16-2-1-11-30(23(16)32)15-6-3-13(25)4-7-15/h3-10,12,16H,1-2,11H2,(H2,27,28)(H,29,31)
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n/an/a 427n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016073
PNG
(CHEMBL3260956)
Show SMILES Nc1nccc(Oc2ccc(NS(=O)(=O)CC(=O)Nc3ccc(F)cc3)cc2F)c1Cl
Show InChI InChI=1S/C19H15ClF2N4O4S/c20-18-16(7-8-24-19(18)23)30-15-6-5-13(9-14(15)22)26-31(28,29)10-17(27)25-12-3-1-11(21)2-4-12/h1-9,26H,10H2,(H2,23,24)(H,25,27)
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n/an/a 433n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50015968
PNG
(CHEMBL3260949)
Show SMILES Cc1ccc(NS(=O)(=O)CC(=O)Nc2ccc(Oc3ccnc(N)c3Cl)c(F)c2)cc1
Show InChI InChI=1S/C20H18ClFN4O4S/c1-12-2-4-13(5-3-12)26-31(28,29)11-18(27)25-14-6-7-16(15(22)10-14)30-17-8-9-24-20(23)19(17)21/h2-10,26H,11H2,1H3,(H2,23,24)(H,25,27)
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n/an/a 495n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50016072
PNG
(CHEMBL3260955)
Show SMILES Cc1ccc(NC(=O)CS(=O)(=O)Nc2ccc(Oc3ccnc(N)c3Cl)c(F)c2)cc1
Show InChI InChI=1S/C20H18ClFN4O4S/c1-12-2-4-13(5-3-12)25-18(27)11-31(28,29)26-14-6-7-16(15(22)10-14)30-17-8-9-24-20(23)19(17)21/h2-10,26H,11H2,1H3,(H2,23,24)(H,25,27)
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n/an/a 1.04E+3n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by ELISA


Eur J Med Chem 80: 254-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.056
BindingDB Entry DOI: 10.7270/Q2930VQ6
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%