Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50044530
TargetCytochrome P450 2C19(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50019934(CHEMBL3287548)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as S-mephenytoin conversion to 4'-hydroxy mephenytoin preincubated for 10 mins followed by N...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50019934(CHEMBL3287548)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as midazolam conversion to 1'-hydroxy midazolam preincubated for 10 mins followed by NADPH ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50019934(CHEMBL3287548)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide conversion to 4-hydroxy tolbutamide preincubated for 10 mins followed by NADPH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50019934(CHEMBL3287548)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as testosterone conversion to 6-hydroxy testosterone preincubated for 10 mins followed by NAD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed