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PubMed code 24944742

Compile data set for download or QSAR
Found 63 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021041
PNG
(CHEMBL3287603)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccn2)c1
Show InChI InChI=1S/C30H26F2N4O5S/c1-42(39,40)18-19-3-2-4-22(15-19)34-27-17-24(11-14-33-27)41-26-10-9-23(16-25(26)32)36-29(38)30(12-13-30)28(37)35-21-7-5-20(31)6-8-21/h2-11,14-17H,12-13,18H2,1H3,(H,33,34)(H,35,37)(H,36,38)
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n/an/a 3.80n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020946
PNG
(CHEMBL3287309)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)c(F)c3)n2)c1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)17-18-3-2-4-21(15-18)34-28-32-14-11-25(36-28)41-22-9-10-24(23(31)16-22)35-27(38)29(12-13-29)26(37)33-20-7-5-19(30)6-8-20/h2-11,14-16H,12-13,17H2,1H3,(H,33,37)(H,35,38)(H,32,34,36)
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n/an/a 4n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50322535
PNG
(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)
Show SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4cccnn34)cc2C(F)(F)F)CC1
Show InChI InChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39)
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n/an/a 4.30n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020950
PNG
(CHEMBL3287313)
Show SMILES COc1cccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(CS(C)(=O)=O)c4)n3)c(F)c2)c1
Show InChI InChI=1S/C30H28FN5O6S/c1-41-23-8-4-7-21(16-23)33-27(37)30(12-13-30)28(38)34-22-9-10-25(24(31)17-22)42-26-11-14-32-29(36-26)35-20-6-3-5-19(15-20)18-43(2,39)40/h3-11,14-17H,12-13,18H2,1-2H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 5.60n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020947
PNG
(CHEMBL3287310)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)c1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)17-18-3-2-4-21(15-18)35-28-32-14-11-25(36-28)41-24-10-9-22(16-23(24)31)34-27(38)29(12-13-29)26(37)33-20-7-5-19(30)6-8-20/h2-11,14-16H,12-13,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 6n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020949
PNG
(CHEMBL3287312)
Show SMILES COc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(CS(C)(=O)=O)c4)n3)c(F)c2)cc1
Show InChI InChI=1S/C30H28FN5O6S/c1-41-23-9-6-20(7-10-23)33-27(37)30(13-14-30)28(38)34-22-8-11-25(24(31)17-22)42-26-12-15-32-29(36-26)35-21-5-3-4-19(16-21)18-43(2,39)40/h3-12,15-17H,13-14,18H2,1-2H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 6.10n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020947
PNG
(CHEMBL3287310)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)c1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)17-18-3-2-4-21(15-18)35-28-32-14-11-25(36-28)41-24-10-9-22(16-23(24)31)34-27(38)29(12-13-29)26(37)33-20-7-5-19(30)6-8-20/h2-11,14-16H,12-13,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 6.70n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020941
PNG
(CHEMBL3287304)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)n2)c1
Show InChI InChI=1S/C29H26FN5O5S/c1-41(38,39)18-19-3-2-4-23(17-19)34-28-31-16-13-25(35-28)40-24-11-9-22(10-12-24)33-27(37)29(14-15-29)26(36)32-21-7-5-20(30)6-8-21/h2-13,16-17H,14-15,18H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 7.90n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020940
PNG
(CHEMBL3287303)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccccc4)cc3)n2)c1
Show InChI InChI=1S/C29H27N5O5S/c1-40(37,38)19-20-6-5-9-23(18-20)33-28-30-17-14-25(34-28)39-24-12-10-22(11-13-24)32-27(36)29(15-16-29)26(35)31-21-7-3-2-4-8-21/h2-14,17-18H,15-16,19H2,1H3,(H,31,35)(H,32,36)(H,30,33,34)
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n/an/a 8.80n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020953
PNG
(CHEMBL3287317)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4cccc(Cl)c4)cc3F)n2)c1
Show InChI InChI=1S/C29H25ClFN5O5S/c1-42(39,40)17-18-4-2-6-20(14-18)35-28-32-13-10-25(36-28)41-24-9-8-22(16-23(24)31)34-27(38)29(11-12-29)26(37)33-21-7-3-5-19(30)15-21/h2-10,13-16H,11-12,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 9.80n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020946
PNG
(CHEMBL3287309)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)c(F)c3)n2)c1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)17-18-3-2-4-21(15-18)34-28-32-14-11-25(36-28)41-22-9-10-24(23(31)16-22)35-27(38)29(12-13-29)26(37)33-20-7-5-19(30)6-8-20/h2-11,14-16H,12-13,17H2,1H3,(H,33,37)(H,35,38)(H,32,34,36)
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n/an/a 13n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020951
PNG
(CHEMBL3287315)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccccc4)cc3F)n2)c1
Show InChI InChI=1S/C29H26FN5O5S/c1-41(38,39)18-19-6-5-9-21(16-19)34-28-31-15-12-25(35-28)40-24-11-10-22(17-23(24)30)33-27(37)29(13-14-29)26(36)32-20-7-3-2-4-8-20/h2-12,15-17H,13-14,18H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 13n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020941
PNG
(CHEMBL3287304)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)n2)c1
Show InChI InChI=1S/C29H26FN5O5S/c1-41(38,39)18-19-3-2-4-23(17-19)34-28-31-16-13-25(35-28)40-24-11-9-22(10-12-24)33-27(37)29(14-15-29)26(36)32-21-7-5-20(30)6-8-21/h2-13,16-17H,14-15,18H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 14n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020940
PNG
(CHEMBL3287303)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccccc4)cc3)n2)c1
Show InChI InChI=1S/C29H27N5O5S/c1-40(37,38)19-20-6-5-9-23(18-20)33-28-30-17-14-25(34-28)39-24-12-10-22(11-13-24)32-27(36)29(15-16-29)26(35)31-21-7-3-2-4-8-21/h2-14,17-18H,15-16,19H2,1H3,(H,31,35)(H,32,36)(H,30,33,34)
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n/an/a 16n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021041
PNG
(CHEMBL3287603)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccn2)c1
Show InChI InChI=1S/C30H26F2N4O5S/c1-42(39,40)18-19-3-2-4-22(15-19)34-27-17-24(11-14-33-27)41-26-10-9-23(16-25(26)32)36-29(38)30(12-13-30)28(37)35-21-7-5-20(31)6-8-21/h2-11,14-17H,12-13,18H2,1H3,(H,33,34)(H,35,37)(H,36,38)
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n/an/a 16n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020944
PNG
(CHEMBL3287307)
Show SMILES Cc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(CS(C)(=O)=O)c4)n3)cc2)cc1
Show InChI InChI=1S/C30H29N5O5S/c1-20-6-8-22(9-7-20)32-27(36)30(15-16-30)28(37)33-23-10-12-25(13-11-23)40-26-14-17-31-29(35-26)34-24-5-3-4-21(18-24)19-41(2,38)39/h3-14,17-18H,15-16,19H2,1-2H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 19n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021040
PNG
(CHEMBL3287601)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ncn2)c1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)16-18-3-2-4-21(13-18)34-25-15-26(33-17-32-25)41-24-10-9-22(14-23(24)31)36-28(38)29(11-12-29)27(37)35-20-7-5-19(30)6-8-20/h2-10,13-15,17H,11-12,16H2,1H3,(H,35,37)(H,36,38)(H,32,33,34)
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n/an/a 22n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020958
PNG
(CHEMBL3287321)
Show SMILES CS(=O)(=O)Cc1ccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)cc1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)17-18-2-6-21(7-3-18)35-28-32-15-12-25(36-28)41-24-11-10-22(16-23(24)31)34-27(38)29(13-14-29)26(37)33-20-8-4-19(30)5-9-20/h2-12,15-16H,13-14,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 23n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021019
PNG
(CHEMBL3287588)
Show SMILES Cc1ccc(CS(C)(=O)=O)cc1Nc1nccc(Oc2ccc(NC(=O)C3(CC3)C(=O)Nc3ccc(F)cc3)cc2F)n1
Show InChI InChI=1S/C30H27F2N5O5S/c1-18-3-4-19(17-43(2,40)41)15-24(18)36-29-33-14-11-26(37-29)42-25-10-9-22(16-23(25)32)35-28(39)30(12-13-30)27(38)34-21-7-5-20(31)6-8-21/h3-11,14-16H,12-13,17H2,1-2H3,(H,34,38)(H,35,39)(H,33,36,37)
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n/an/a 25n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020951
PNG
(CHEMBL3287315)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccccc4)cc3F)n2)c1
Show InChI InChI=1S/C29H26FN5O5S/c1-41(38,39)18-19-6-5-9-21(16-19)34-28-31-15-12-25(35-28)40-24-11-10-22(17-23(24)30)33-27(37)29(13-14-29)26(36)32-20-7-3-2-4-8-20/h2-12,15-17H,13-14,18H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 26n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020942
PNG
(CHEMBL3287305)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(Cl)cc4)cc3)n2)c1
Show InChI InChI=1S/C29H26ClN5O5S/c1-41(38,39)18-19-3-2-4-23(17-19)34-28-31-16-13-25(35-28)40-24-11-9-22(10-12-24)33-27(37)29(14-15-29)26(36)32-21-7-5-20(30)6-8-21/h2-13,16-17H,14-15,18H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 30n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020942
PNG
(CHEMBL3287305)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(Cl)cc4)cc3)n2)c1
Show InChI InChI=1S/C29H26ClN5O5S/c1-41(38,39)18-19-3-2-4-23(17-19)34-28-31-16-13-25(35-28)40-24-11-9-22(10-12-24)33-27(37)29(14-15-29)26(36)32-21-7-5-20(30)6-8-21/h2-13,16-17H,14-15,18H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 33n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020952
PNG
(CHEMBL3287316)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4cccc(F)c4)cc3F)n2)c1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)17-18-4-2-6-20(14-18)35-28-32-13-10-25(36-28)41-24-9-8-22(16-23(24)31)34-27(38)29(11-12-29)26(37)33-21-7-3-5-19(30)15-21/h2-10,13-16H,11-12,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 43n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020956
PNG
(CHEMBL3287320)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(C#N)c(c4)C(F)(F)F)cc3F)n2)c1
Show InChI InChI=1S/C31H24F4N6O5S/c1-47(44,45)17-18-3-2-4-20(13-18)40-29-37-12-9-26(41-29)46-25-8-7-22(15-24(25)32)39-28(43)30(10-11-30)27(42)38-21-6-5-19(16-36)23(14-21)31(33,34)35/h2-9,12-15H,10-11,17H2,1H3,(H,38,42)(H,39,43)(H,37,40,41)
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n/an/a 45n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020957
PNG
(CHEMBL3287590)
Show SMILES CS(=O)(=O)Cn1ccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)n1
Show InChI InChI=1S/C26H23F2N7O5S/c1-41(38,39)15-35-13-9-21(34-35)32-25-29-12-8-22(33-25)40-20-7-6-18(14-19(20)28)31-24(37)26(10-11-26)23(36)30-17-4-2-16(27)3-5-17/h2-9,12-14H,10-11,15H2,1H3,(H,30,36)(H,31,37)(H,29,32,33,34)
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n/an/a 45n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020948
PNG
(CHEMBL3287311)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(Br)cc4)cc3F)n2)c1
Show InChI InChI=1S/C29H25BrFN5O5S/c1-42(39,40)17-18-3-2-4-21(15-18)35-28-32-14-11-25(36-28)41-24-10-9-22(16-23(24)31)34-27(38)29(12-13-29)26(37)33-20-7-5-19(30)6-8-20/h2-11,14-16H,12-13,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 47n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020954
PNG
(CHEMBL3287318)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4cccc(c4)C(F)(F)F)cc3F)n2)c1
Show InChI InChI=1S/C30H25F4N5O5S/c1-45(42,43)17-18-4-2-6-20(14-18)38-28-35-13-10-25(39-28)44-24-9-8-22(16-23(24)31)37-27(41)29(11-12-29)26(40)36-21-7-3-5-19(15-21)30(32,33)34/h2-10,13-16H,11-12,17H2,1H3,(H,36,40)(H,37,41)(H,35,38,39)
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n/an/a 48n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020958
PNG
(CHEMBL3287321)
Show SMILES CS(=O)(=O)Cc1ccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)cc1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)17-18-2-6-21(7-3-18)35-28-32-15-12-25(36-28)41-24-11-10-22(16-23(24)31)34-27(38)29(13-14-29)26(37)33-20-8-4-19(30)5-9-20/h2-12,15-16H,13-14,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 52n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021021
PNG
(CHEMBL3287592)
Show SMILES CC(=O)c1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)c1
Show InChI InChI=1S/C29H23F2N5O4/c1-17(37)18-3-2-4-21(15-18)35-28-32-14-11-25(36-28)40-24-10-9-22(16-23(24)31)34-27(39)29(12-13-29)26(38)33-20-7-5-19(30)6-8-20/h2-11,14-16H,12-13H2,1H3,(H,33,38)(H,34,39)(H,32,35,36)
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n/an/a 52n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021028
PNG
(CHEMBL3287596)
Show SMILES COc1ccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)cc1
Show InChI InChI=1S/C28H23F2N5O4/c1-38-21-9-6-19(7-10-21)34-27-31-15-12-24(35-27)39-23-11-8-20(16-22(23)30)33-26(37)28(13-14-28)25(36)32-18-4-2-17(29)3-5-18/h2-12,15-16H,13-14H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 53n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020944
PNG
(CHEMBL3287307)
Show SMILES Cc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(CS(C)(=O)=O)c4)n3)cc2)cc1
Show InChI InChI=1S/C30H29N5O5S/c1-20-6-8-22(9-7-20)32-27(36)30(15-16-30)28(37)33-23-10-12-25(13-11-23)40-26-14-17-31-29(35-26)34-24-5-3-4-21(18-24)19-41(2,38)39/h3-14,17-18H,15-16,19H2,1-2H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 54n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021040
PNG
(CHEMBL3287601)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ncn2)c1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)16-18-3-2-4-21(13-18)34-25-15-26(33-17-32-25)41-24-10-9-22(14-23(24)31)36-28(38)29(11-12-29)27(37)35-20-7-5-19(30)6-8-20/h2-10,13-15,17H,11-12,16H2,1H3,(H,35,37)(H,36,38)(H,32,33,34)
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n/an/a 55n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020943
PNG
(CHEMBL3287306)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(Br)cc4)cc3)n2)c1
Show InChI InChI=1S/C29H26BrN5O5S/c1-41(38,39)18-19-3-2-4-23(17-19)34-28-31-16-13-25(35-28)40-24-11-9-22(10-12-24)33-27(37)29(14-15-29)26(36)32-21-7-5-20(30)6-8-21/h2-13,16-17H,14-15,18H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 62n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020943
PNG
(CHEMBL3287306)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(Br)cc4)cc3)n2)c1
Show InChI InChI=1S/C29H26BrN5O5S/c1-41(38,39)18-19-3-2-4-23(17-19)34-28-31-16-13-25(35-28)40-24-11-9-22(10-12-24)33-27(37)29(14-15-29)26(36)32-21-7-5-20(30)6-8-21/h2-13,16-17H,14-15,18H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 66n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021020
PNG
(CHEMBL3287591)
Show SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4ccccc4)n3)c(F)c2)cc1
Show InChI InChI=1S/C27H21F2N5O3/c28-17-6-8-19(9-7-17)31-24(35)27(13-14-27)25(36)32-20-10-11-22(21(29)16-20)37-23-12-15-30-26(34-23)33-18-4-2-1-3-5-18/h1-12,15-16H,13-14H2,(H,31,35)(H,32,36)(H,30,33,34)
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n/an/a 68n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020948
PNG
(CHEMBL3287311)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(Br)cc4)cc3F)n2)c1
Show InChI InChI=1S/C29H25BrFN5O5S/c1-42(39,40)17-18-3-2-4-21(15-18)35-28-32-14-11-25(36-28)41-24-10-9-22(16-23(24)31)34-27(38)29(12-13-29)26(37)33-20-7-5-19(30)6-8-20/h2-11,14-16H,12-13,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 71n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021042
PNG
(CHEMBL3287314)
Show SMILES Cc1cccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(CS(C)(=O)=O)c4)n3)c(F)c2)c1
Show InChI InChI=1S/C30H28FN5O5S/c1-19-5-3-7-21(15-19)33-27(37)30(12-13-30)28(38)34-23-9-10-25(24(31)17-23)41-26-11-14-32-29(36-26)35-22-8-4-6-20(16-22)18-42(2,39)40/h3-11,14-17H,12-13,18H2,1-2H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 82n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020955
PNG
(CHEMBL3287319)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)cc3F)n2)c1
Show InChI InChI=1S/C30H24ClF4N5O5S/c1-46(43,44)16-17-3-2-4-18(13-17)39-28-36-12-9-25(40-28)45-24-8-6-20(15-23(24)32)38-27(42)29(10-11-29)26(41)37-19-5-7-22(31)21(14-19)30(33,34)35/h2-9,12-15H,10-11,16H2,1H3,(H,37,41)(H,38,42)(H,36,39,40)
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n/an/a 84n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021043
PNG
(CHEMBL3287593)
Show SMILES [O-][N+](=O)c1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)c1
Show InChI InChI=1S/C27H20F2N6O5/c28-16-4-6-17(7-5-16)31-24(36)27(11-12-27)25(37)32-19-8-9-22(21(29)15-19)40-23-10-13-30-26(34-23)33-18-2-1-3-20(14-18)35(38)39/h1-10,13-15H,11-12H2,(H,31,36)(H,32,37)(H,30,33,34)
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n/an/a 105n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021022
PNG
(CHEMBL3287595)
Show SMILES COc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)c1
Show InChI InChI=1S/C28H23F2N5O4/c1-38-21-4-2-3-19(15-21)34-27-31-14-11-24(35-27)39-23-10-9-20(16-22(23)30)33-26(37)28(12-13-28)25(36)32-18-7-5-17(29)6-8-18/h2-11,14-16H,12-13H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 114n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021019
PNG
(CHEMBL3287588)
Show SMILES Cc1ccc(CS(C)(=O)=O)cc1Nc1nccc(Oc2ccc(NC(=O)C3(CC3)C(=O)Nc3ccc(F)cc3)cc2F)n1
Show InChI InChI=1S/C30H27F2N5O5S/c1-18-3-4-19(17-43(2,40)41)15-24(18)36-29-33-14-11-26(37-29)42-25-10-9-22(16-23(25)32)35-28(39)30(12-13-30)27(38)34-21-7-5-20(31)6-8-21/h3-11,14-16H,12-13,17H2,1-2H3,(H,34,38)(H,35,39)(H,33,36,37)
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n/an/a 150n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020952
PNG
(CHEMBL3287316)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4cccc(F)c4)cc3F)n2)c1
Show InChI InChI=1S/C29H25F2N5O5S/c1-42(39,40)17-18-4-2-6-20(14-18)35-28-32-13-10-25(36-28)41-24-9-8-22(16-23(24)31)34-27(38)29(11-12-29)26(37)33-21-7-3-5-19(30)15-21/h2-10,13-16H,11-12,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 155n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021048
PNG
(CHEMBL3287600)
Show SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(NC4CC4)n3)c(F)c2)cc1
Show InChI InChI=1S/C24H21F2N5O3/c25-14-1-3-15(4-2-14)28-21(32)24(10-11-24)22(33)29-17-7-8-19(18(26)13-17)34-20-9-12-27-23(31-20)30-16-5-6-16/h1-4,7-9,12-13,16H,5-6,10-11H2,(H,28,32)(H,29,33)(H,27,30,31)
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n/an/a 169n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021021
PNG
(CHEMBL3287592)
Show SMILES CC(=O)c1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)c1
Show InChI InChI=1S/C29H23F2N5O4/c1-17(37)18-3-2-4-21(15-18)35-28-32-14-11-25(36-28)40-24-10-9-22(16-23(24)31)34-27(39)29(12-13-29)26(38)33-20-7-5-19(30)6-8-20/h2-11,14-16H,12-13H2,1H3,(H,33,38)(H,34,39)(H,32,35,36)
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n/an/a 181n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020945
PNG
(CHEMBL3287308)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(cc4)C(F)(F)F)cc3)n2)c1
Show InChI InChI=1S/C30H26F3N5O5S/c1-44(41,42)18-19-3-2-4-23(17-19)37-28-34-16-13-25(38-28)43-24-11-9-22(10-12-24)36-27(40)29(14-15-29)26(39)35-21-7-5-20(6-8-21)30(31,32)33/h2-13,16-17H,14-15,18H2,1H3,(H,35,39)(H,36,40)(H,34,37,38)
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n/an/a 184n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021035
PNG
(CHEMBL3287597)
Show SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(c4)C(F)(F)F)n3)c(F)c2)cc1
Show InChI InChI=1S/C28H20F5N5O3/c29-17-4-6-18(7-5-17)35-24(39)27(11-12-27)25(40)36-20-8-9-22(21(30)15-20)41-23-10-13-34-26(38-23)37-19-3-1-2-16(14-19)28(31,32)33/h1-10,13-15H,11-12H2,(H,35,39)(H,36,40)(H,34,37,38)
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n/an/a 187n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021035
PNG
(CHEMBL3287597)
Show SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(c4)C(F)(F)F)n3)c(F)c2)cc1
Show InChI InChI=1S/C28H20F5N5O3/c29-17-4-6-18(7-5-17)35-24(39)27(11-12-27)25(40)36-20-8-9-22(21(30)15-20)41-23-10-13-34-26(38-23)37-19-3-1-2-16(14-19)28(31,32)33/h1-10,13-15H,11-12H2,(H,35,39)(H,36,40)(H,34,37,38)
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n/an/a 196n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021052
PNG
(CHEMBL3287605)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)cc(n2)C(N)=O)c1
Show InChI InChI=1S/C31H27F2N5O6S/c1-45(42,43)17-18-3-2-4-21(13-18)35-27-16-23(15-25(38-27)28(34)39)44-26-10-9-22(14-24(26)33)37-30(41)31(11-12-31)29(40)36-20-7-5-19(32)6-8-20/h2-10,13-16H,11-12,17H2,1H3,(H2,34,39)(H,35,38)(H,36,40)(H,37,41)
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n/an/a 211n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020953
PNG
(CHEMBL3287317)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4cccc(Cl)c4)cc3F)n2)c1
Show InChI InChI=1S/C29H25ClFN5O5S/c1-42(39,40)17-18-4-2-6-20(14-18)35-28-32-13-10-25(36-28)41-24-9-8-22(16-23(24)31)34-27(38)29(11-12-29)26(37)33-21-7-3-5-19(30)15-21/h2-10,13-16H,11-12,17H2,1H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 213n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50020945
PNG
(CHEMBL3287308)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(cc4)C(F)(F)F)cc3)n2)c1
Show InChI InChI=1S/C30H26F3N5O5S/c1-44(41,42)18-19-3-2-4-23(17-19)37-28-34-16-13-25(38-28)43-24-11-9-22(10-12-24)36-27(40)29(14-15-29)26(39)35-21-7-5-20(6-8-21)30(31,32)33/h2-13,16-17H,14-15,18H2,1H3,(H,35,39)(H,36,40)(H,34,37,38)
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n/an/a 220n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021022
PNG
(CHEMBL3287595)
Show SMILES COc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)c1
Show InChI InChI=1S/C28H23F2N5O4/c1-38-21-4-2-3-19(15-21)34-27-31-14-11-24(35-27)39-23-10-9-20(16-22(23)30)33-26(37)28(12-13-28)25(36)32-18-7-5-17(29)6-8-18/h2-11,14-16H,12-13H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 230n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020954
PNG
(CHEMBL3287318)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4cccc(c4)C(F)(F)F)cc3F)n2)c1
Show InChI InChI=1S/C30H25F4N5O5S/c1-45(42,43)17-18-4-2-6-20(14-18)38-28-35-13-10-25(39-28)44-24-9-8-22(16-23(24)31)37-27(41)29(11-12-29)26(40)36-21-7-3-5-19(15-21)30(32,33)34/h2-10,13-16H,11-12,17H2,1H3,(H,36,40)(H,37,41)(H,35,38,39)
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n/an/a 234n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021037
PNG
(CHEMBL3287599)
Show SMILES CCOCCNc1nccc(Oc2ccc(NC(=O)C3(CC3)C(=O)Nc3ccc(F)cc3)cc2F)n1
Show InChI InChI=1S/C25H25F2N5O4/c1-2-35-14-13-29-24-28-12-9-21(32-24)36-20-8-7-18(15-19(20)27)31-23(34)25(10-11-25)22(33)30-17-5-3-16(26)4-6-17/h3-9,12,15H,2,10-11,13-14H2,1H3,(H,30,33)(H,31,34)(H,28,29,32)
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n/an/a 249n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021020
PNG
(CHEMBL3287591)
Show SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4ccccc4)n3)c(F)c2)cc1
Show InChI InChI=1S/C27H21F2N5O3/c28-17-6-8-19(9-7-17)31-24(35)27(13-14-27)25(36)32-20-10-11-22(21(29)16-20)37-23-12-15-30-26(34-23)33-18-4-2-1-3-5-18/h1-12,15-16H,13-14H2,(H,31,35)(H,32,36)(H,30,33,34)
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n/an/a 256n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020949
PNG
(CHEMBL3287312)
Show SMILES COc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(CS(C)(=O)=O)c4)n3)c(F)c2)cc1
Show InChI InChI=1S/C30H28FN5O6S/c1-41-23-9-6-20(7-10-23)33-27(37)30(13-14-30)28(38)34-22-8-11-25(24(31)17-22)42-26-12-15-32-29(36-26)35-21-5-3-4-19(16-21)18-43(2,39)40/h3-12,15-17H,13-14,18H2,1-2H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 338n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021045
PNG
(CHEMBL3287594)
Show SMILES [O-][N+](=O)c1ccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)cc1
Show InChI InChI=1S/C27H20F2N6O5/c28-16-1-3-17(4-2-16)31-24(36)27(12-13-27)25(37)32-19-7-10-22(21(29)15-19)40-23-11-14-30-26(34-23)33-18-5-8-20(9-6-18)35(38)39/h1-11,14-15H,12-13H2,(H,31,36)(H,32,37)(H,30,33,34)
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n/an/a 643n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020950
PNG
(CHEMBL3287313)
Show SMILES COc1cccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4cccc(CS(C)(=O)=O)c4)n3)c(F)c2)c1
Show InChI InChI=1S/C30H28FN5O6S/c1-41-23-8-4-7-21(16-23)33-27(37)30(12-13-30)28(38)34-22-9-10-25(24(31)17-22)42-26-11-14-32-29(36-26)35-20-6-3-5-19(15-20)18-43(2,39)40/h3-11,14-17H,12-13,18H2,1-2H3,(H,33,37)(H,34,38)(H,32,35,36)
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n/an/a 683n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50020955
PNG
(CHEMBL3287319)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)cc3F)n2)c1
Show InChI InChI=1S/C30H24ClF4N5O5S/c1-46(43,44)16-17-3-2-4-18(13-17)39-28-36-12-9-25(40-28)45-24-8-6-20(15-23(24)32)38-27(42)29(10-11-29)26(41)37-19-5-7-22(31)21(14-19)30(33,34)35/h2-9,12-15H,10-11,16H2,1H3,(H,37,41)(H,38,42)(H,36,39,40)
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n/an/a 792n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021051
PNG
(CHEMBL3287604)
Show SMILES CS(=O)(=O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)cc(n2)C#N)c1
Show InChI InChI=1S/C31H25F2N5O5S/c1-44(41,42)18-19-3-2-4-22(13-19)35-28-16-25(14-24(17-34)36-28)43-27-10-9-23(15-26(27)33)38-30(40)31(11-12-31)29(39)37-21-7-5-20(32)6-8-21/h2-10,13-16H,11-12,18H2,1H3,(H,35,36)(H,37,39)(H,38,40)
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n/an/a 806n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50021050
PNG
(CHEMBL3287602)
Show SMILES Cc1nc(Nc2cccc(CS(C)(=O)=O)c2)cc(Oc2ccc(NC(=O)C3(CC3)C(=O)Nc3ccc(F)cc3)cc2F)n1
Show InChI InChI=1S/C30H27F2N5O5S/c1-18-33-26(35-22-5-3-4-19(14-22)17-43(2,40)41)16-27(34-18)42-25-11-10-23(15-24(25)32)37-29(39)30(12-13-30)28(38)36-21-8-6-20(31)7-9-21/h3-11,14-16H,12-13,17H2,1-2H3,(H,36,38)(H,37,39)(H,33,34,35)
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n/an/a 924n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021037
PNG
(CHEMBL3287599)
Show SMILES CCOCCNc1nccc(Oc2ccc(NC(=O)C3(CC3)C(=O)Nc3ccc(F)cc3)cc2F)n1
Show InChI InChI=1S/C25H25F2N5O4/c1-2-35-14-13-29-24-28-12-9-21(32-24)36-20-8-7-18(15-19(20)27)31-23(34)25(10-11-25)22(33)30-17-5-3-16(26)4-6-17/h3-9,12,15H,2,10-11,13-14H2,1H3,(H,30,33)(H,31,34)(H,28,29,32)
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n/an/a 2.47E+3n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021036
PNG
(CHEMBL3287598)
Show SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc(Nc4ccc(C#N)c(c4)C(F)(F)F)n3)c(F)c2)cc1
Show InChI InChI=1S/C29H19F5N6O3/c30-17-2-5-18(6-3-17)37-25(41)28(10-11-28)26(42)38-20-7-8-23(22(31)14-20)43-24-9-12-36-27(40-24)39-19-4-1-16(15-35)21(13-19)29(32,33)34/h1-9,12-14H,10-11H2,(H,37,41)(H,38,42)(H,36,39,40)
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n/an/a 2.72E+3n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50021028
PNG
(CHEMBL3287596)
Show SMILES COc1ccc(Nc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)n2)cc1
Show InChI InChI=1S/C28H23F2N5O4/c1-38-21-9-6-19(7-10-21)34-27-31-15-12-24(35-27)39-23-11-8-20(16-22(23)30)33-26(37)28(13-14-28)25(36)32-18-4-2-17(29)3-5-18/h2-12,15-16H,13-14H2,1H3,(H,32,36)(H,33,37)(H,31,34,35)
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n/an/a 4.39E+3n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


ACS Med Chem Lett 5: 673-8 (2014)


Article DOI: 10.1021/ml500066m
BindingDB Entry DOI: 10.7270/Q2FX7C1M
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%