Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with all data for entry = 50001643
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50016901((2-Methyl-3-oxo-3H-phenalen-1-yl)-acetic acid | CH...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  540nMAssay Description:Inhibition of aldose reductase (or polyol accumulation) in isolated rat sciatic nerve by compound at 10e-5 M concentrationMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50016902(CHEMBL168106 | [Methyl-(naphthalene-1-carbothioyl)...)
Affinity DataIC50:  730nMAssay Description:In vitro inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50016901((2-Methyl-3-oxo-3H-phenalen-1-yl)-acetic acid | CH...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of aldose reductase (or polyol accumulation) in isolated rat sciatic nerve by compound at (10E-5) M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed