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PubMed code 25516794

Compile data set for download or QSAR
Found 71 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 2C9


(Homo sapiens (human))
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/a 8.50E+3n/an/an/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2C9 (unknown origin)


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Cytochrome P450 2C9


(Homo sapiens (human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2C9 (unknown origin)


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Cytochrome P450 1A


(Homo sapiens (human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP1A2 (unknown origin)


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Cytochrome P450 2C19


(Homo sapiens (human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2C19 (unknown origin)


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6 (unknown origin)


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Cytochrome P450 3A


(Homo sapiens (human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP3A4 (unknown origin)


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (human))
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a 8.60E+3n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a 85n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Macaca mulatta)
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a 0.0380n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at monkey S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041986
PNG
(CHEMBL3359517)
Show SMILES COc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C22H20N2O4/c1-27-21-5-2-14(8-17(21)12-23)13-28-18-3-4-19-16(9-18)10-20-15(11-22(25)26)6-7-24(19)20/h2-5,8-10,15H,6-7,11,13H2,1H3,(H,25,26)
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n/an/an/an/a 38n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 2.5n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 40n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 8.60n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 20n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Macaca mulatta)
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a 0.0580n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at monkey S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041985
PNG
(CHEMBL3359518)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(OCF)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C22H19F4NO4/c23-12-31-20-4-1-13(7-17(20)22(24,25)26)11-30-16-2-3-18-15(8-16)9-19-14(10-21(28)29)5-6-27(18)19/h1-4,7-9,14H,5-6,10-12H2,(H,28,29)
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n/an/an/an/a 6.70n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 0.0950n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 5


(Homo sapiens (human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a 410n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 5


(Homo sapiens (human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 107n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a 0.130n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 5


(Homo sapiens (human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 5


(Homo sapiens (human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a 19n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine-1-phosphate receptor 1


(Canis lupus familiaris)
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a 0.0490n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at dog S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a 0.0210n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041987
PNG
(CHEMBL3359516)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C#N)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C22H17F3N2O3/c23-22(24,25)18-7-13(1-2-15(18)11-26)12-30-17-3-4-19-16(8-17)9-20-14(10-21(28)29)5-6-27(19)20/h1-4,7-9,14H,5-6,10,12H2,(H,28,29)
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n/an/an/an/a 83n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 0.0410n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 420n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 0.640n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 0.0670n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine-1-phosphate receptor 1


(Canis lupus familiaris)
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a 0.0490n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at dog S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a 0.150n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 5


(Homo sapiens (human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a 9.80E+3n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 5


(Homo sapiens (human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a 1.5n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 0.320n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a 0.0500n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at mouse S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Rattus norvegicus)
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a 0.0500n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a 0.620n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041984
PNG
(CHEMBL3359521)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(OCC4CC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C25H24F3NO4/c26-25(27,28)20-9-16(3-6-23(20)33-13-15-1-2-15)14-32-19-4-5-21-18(10-19)11-22-17(12-24(30)31)7-8-29(21)22/h3-6,9-11,15,17H,1-2,7-8,12-14H2,(H,30,31)
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n/an/an/an/a 1.10n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041989
PNG
(CHEMBL3359514)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C#N)ccc21
Show InChI InChI=1S/C26H26N2O3/c27-15-21-11-17(5-7-23(21)18-3-1-2-4-18)16-31-22-6-8-24-20(12-22)13-25-19(14-26(29)30)9-10-28(24)25/h5-8,11-13,18-19H,1-4,9-10,14,16H2,(H,29,30)
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n/an/an/an/a 0.490n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a 160n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 5


(Homo sapiens (human))
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a 47n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a 0.630n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 0.150n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a 11n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (human))
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a 0.0250n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 570n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM50041979
PNG
(CHEMBL3359520)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1S/C24H24N2O4/c1-15(2)30-23-6-3-16(9-19(23)13-25)14-29-20-4-5-21-18(10-20)11-22-17(12-24(27)28)7-8-26(21)22/h3-6,9-11,15,17H,7-8,12,14H2,1-2H3,(H,27,28)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (human))
BDBM50041980
PNG
(CHEMBL3359519)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM50041983
PNG
(CHEMBL3359523)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO4/c1-13(2)33-20-6-3-14(9-18(20)24(26,27)28)12-32-16-4-5-19-17(11-16)22(25)23-15(10-21(30)31)7-8-29(19)23/h3-6,9,11,13,15H,7-8,10,12H2,1-2H3,(H,30,31)/t15-/m1/s1
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n/an/an/an/a 0.0640n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at mouse S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Rattus norvegicus)
BDBM50041982
PNG
(CHEMBL3359522)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CC[C@H](CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
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n/an/an/an/a 0.0720n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM50041988
PNG
(CHEMBL3359515)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(Cl)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C21H17ClF3NO3/c22-17-3-1-12(7-16(17)21(23,24)25)11-29-15-2-4-18-14(8-15)9-19-13(10-20(27)28)5-6-26(18)19/h1-4,7-9,13H,5-6,10-11H2,(H,27,28)
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n/an/an/an/a 150n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 5


(Homo sapiens (human))
BDBM50041981
PNG
(CHEMBL3358955)
Show SMILES OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-16(5-7-21(22)17-3-1-2-4-17)15-33-20-6-8-23-19(12-20)13-24-18(14-25(31)32)9-10-30(23)24/h5-8,11-13,17-18H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 81n/an/an/an/a



Arena Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


ACS Med Chem Lett 5: 1334-9 (2014)


Article DOI: 10.1021/ml500422m
BindingDB Entry DOI: 10.7270/Q2XK8H6S
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%