Compile Data Set for Download or QSAR
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Found 50 Enz. Inhib. hit(s) with all data for entry = 50035810
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017495(2-Benzo[b]thiophen-4-yl-N-[2-(3-hydroxymethyl-pyrr...)
Affinity DataKi:  7nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017500(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017488(2-Benzofuran-4-yl-N-(4,5-dimethoxy-2-pyrrolidin-1-...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017494(2-Benzo[b]thiophen-7-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017498(2-Benzofuran-4-yl-N-[2-(3-hydroxymethyl-pyrrolidin...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50013147(2-Benzo[b]thiophen-4-yl-N-(4,5-dimethoxy-2-pyrroli...)
Affinity DataKi:  18nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017504(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  53nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017499(2-Benzo[b]thiophen-3-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  69nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  86nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017489(2-Benzo[b]thiophen-5-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  94nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50452622(CHEMBL2093981)
Affinity DataKi: >100nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017501(2-Benzo[b]thiophen-6-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  146nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017497(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  154nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017510(CHEMBL540277 | Succinic acid bis-(1-{2-[(2-benzofu...)
Affinity DataKi:  180nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017507(CHEMBL553665 | Pentanedioic acid bis-(1-{2-[(2-ben...)
Affinity DataKi:  180nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017492(Benzo[b]thiophen-4-yl-acetic acid 2-pyrrolidin-1-y...)
Affinity DataKi:  261nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017505(2-Benzo[b]thiophen-4-yl-N-(2-pyrrolidin-1-yl-cyclo...)
Affinity DataKi:  333nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  410nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017501(2-Benzo[b]thiophen-6-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  425nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017489(2-Benzo[b]thiophen-5-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  475nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017495(2-Benzo[b]thiophen-4-yl-N-[2-(3-hydroxymethyl-pyrr...)
Affinity DataKi:  560nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017494(2-Benzo[b]thiophen-7-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  650nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017504(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017507(CHEMBL553665 | Pentanedioic acid bis-(1-{2-[(2-ben...)
Affinity DataKi:  760nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017510(CHEMBL540277 | Succinic acid bis-(1-{2-[(2-benzofu...)
Affinity DataKi:  800nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017503(2-(1H-Indol-4-yl)-N-methyl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  816nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017488(2-Benzofuran-4-yl-N-(4,5-dimethoxy-2-pyrrolidin-1-...)
Affinity DataKi:  820nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017503(2-(1H-Indol-4-yl)-N-methyl-N-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  833nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017500(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50452622(CHEMBL2093981)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017499(2-Benzo[b]thiophen-3-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017493(2-Benzo[b]thiophen-4-yl-N-pentyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50013147(2-Benzo[b]thiophen-4-yl-N-(4,5-dimethoxy-2-pyrroli...)
Affinity DataKi:  2.80E+3nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017492(Benzo[b]thiophen-4-yl-acetic acid 2-pyrrolidin-1-y...)
Affinity DataKi:  3.34E+3nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017497(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017498(2-Benzofuran-4-yl-N-[2-(3-hydroxymethyl-pyrrolidin...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017505(2-Benzo[b]thiophen-4-yl-N-(2-pyrrolidin-1-yl-cyclo...)
Affinity DataKi:  4.80E+3nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017493(2-Benzo[b]thiophen-4-yl-N-pentyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  5.20E+3nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017490((2-Benzo[b]thiophen-4-yl-ethyl)-methyl-(2-pyrrolid...)
Affinity DataKi:  8.10E+3nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017496(2-Benzo[b]thiophen-4-yl-N-(2-pyrrolidin-1-yl-ethyl...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50452623(CHEMBL2094047)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50452623(CHEMBL2094047)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017490((2-Benzo[b]thiophen-4-yl-ethyl)-methyl-(2-pyrrolid...)
Affinity DataKi:  1.43E+4nMAssay Description:Binding affinity towards opioid receptor mu was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017506(2-Benzo[b]thiophen-4-yl-1-(decahydro-pyrrolo[1,2-a...)
Affinity DataKi:  1.75E+4nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017509(2-Pyrrolidin-1-yl-cyclohexanecarboxylic acid benzo...)
Affinity DataKi:  2.03E+4nMAssay Description:Binding affinity towards mu opioid receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017496(2-Benzo[b]thiophen-4-yl-N-(2-pyrrolidin-1-yl-ethyl...)
Affinity DataKi:  2.50E+4nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017506(2-Benzo[b]thiophen-4-yl-1-(decahydro-pyrrolo[1,2-a...)
Affinity DataKi:  2.80E+4nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50017509(2-Pyrrolidin-1-yl-cyclohexanecarboxylic acid benzo...)
Affinity DataKi:  3.70E+4nMAssay Description:Binding affinity towards Opioid receptor kappa 1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed