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Found 12 Enz. Inhib. hit(s) with all data for entry = 50045503
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065429(CHEMBL3401357)
Affinity DataEC50:  9.13E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065430(CHEMBL3401356)
Affinity DataEC50:  730nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065431(CHEMBL3401355)
Affinity DataEC50:  1.49E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065432(CHEMBL3401354)
Affinity DataEC50:  580nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065433(CHEMBL3401353)
Affinity DataEC50:  750nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50236238((3alpha,5beta)-3-hydroxycholan-24-oic acid | 3alph...)
Affinity DataEC50:  680nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065435(CHEMBL3401351)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM21676((2S,4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-di...)
Affinity DataEC50:  2.83E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065436(3,7-diketone | CHEMBL1254261)
Affinity DataEC50:  1.09E+4nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM21674((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...)
Affinity DataEC50:  6.10E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM53721((4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-10,13-dim...)
Affinity DataEC50:  2.39E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065434(CHEMBL3401352)
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed