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Found 2 Enz. Inhib. hit(s) with all data for entry = 50046686
TargetDNA topoisomerase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50125944(CHEMBL3627832)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant topoisomerase 1 assessed as blocking of supercoiled pHOT DNA relaxation incubated for 25 mins at 37 degC by ethidium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50125944(CHEMBL3627832)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant topoisomerase 2 alpha assessed as blocking of supercoiled pHOT DNA relaxation incubated for 45 mins at 37 degC by eth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed