Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 7019
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM166682((2R)-2-[[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)pi...)
Affinity DataIC50:  167nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM166683(U74389G (B9))
Affinity DataIC50:  174nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM50451094(Ascorbyl Palmitate | Ascorbyl palmitate (E5) | E30...)
Affinity DataIC50:  600nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM166685(Octyl (2E)‐3‐(3,4‐dihydroxypheny...)
Affinity DataIC50:  840nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM166686(2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-di...)
Affinity DataIC50:  1.08E+3nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  1.23E+3nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM81348(β-Lapachone (A3) | Beta lapachone | R115 (Rea...)
Affinity DataIC50:  1.69E+3nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50:  1.80E+3nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)
Affinity DataIC50:  2.23E+3nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataIC50:  4.04E+3nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM50210259((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hex...)
Affinity DataIC50:  6.76E+3nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM31752(Icosa‐5,8,11,14‐tetraynoic acid (D3) |...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 無 total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed