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Found 2 Enz. Inhib. hit(s) with all data for entry = 50045877
TargetDNA topoisomerase 1(Homo sapiens (Human))
Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50087878(CHEMBL3426919)
Affinity DataIC50:  670nMAssay Description:Inhibition of human topoisomerase 1-mediated DNA cleavage assessed as accumulation of nicked DNA by ethidium bromide staining based electrophoregramMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50087876(CHEMBL3426918)
Affinity DataIC50:  810nMAssay Description:Inhibition of human topoisomerase 1-mediated DNA cleavage assessed as accumulation of nicked DNA by ethidium bromide staining based electrophoregramMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed