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Found 13 Enz. Inhib. hit(s) with all data for entry = 7021
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166702(5-(4-chlorophenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...)
Affinity DataIC50:  4.50E+3nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166703(5-(2-chlorophenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...)
Affinity DataIC50:  5.35E+3nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166704(5-(2-bromophenyl)-3-[5-hydroxy-4-pyrone-2-yl-methy...)
Affinity DataIC50:  5.98E+3nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166697(5-(4-methylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...)
Affinity DataIC50:  6.25E+3nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166698(5-(3-methylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...)
Affinity DataIC50:  6.82E+3nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166699(5-(2-methylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...)
Affinity DataIC50:  7.12E+3nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166696(5-phenyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto...)
Affinity DataIC50:  7.45E+3nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166700(5-(4-methoxylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-me...)
Affinity DataIC50:  1.12E+4nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166701(5-(2-methoxylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-me...)
Affinity DataIC50:  1.32E+4nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.90E+4nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166694(5-ethyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto]...)
Affinity DataIC50:  2.57E+4nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166695(5-propyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto...)
Affinity DataIC50:  2.82E+4nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUncharacterized protein YOR062C(Agaricus bisporus (Mushroom))
Hunan University Of Science And Technology

LigandPNGBDBM166693(5-methyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto...)
Affinity DataIC50:  9.10E+4nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed