BindingDB logo
myBDB logout

PubMed code 26002335

Compile data set for download or QSAR
Found 55 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50414921
PNG
(CHEMBL570812)
Show SMILES COc1nn(-c2ccc(NC(=O)OCc3ccccc3)c(C)c2)c(=O)o1
Show InChI InChI=1S/C18H17N3O5/c1-12-10-14(21-18(23)26-17(20-21)24-2)8-9-15(12)19-16(22)25-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3,(H,19,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 60 mins followed by substrate addition b...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50414921
PNG
(CHEMBL570812)
Show SMILES COc1nn(-c2ccc(NC(=O)OCc3ccccc3)c(C)c2)c(=O)o1
Show InChI InChI=1S/C18H17N3O5/c1-12-10-14(21-18(23)26-17(20-21)24-2)8-9-15(12)19-16(22)25-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3,(H,19,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.5n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 30 mins followed by substrate addition b...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM26739
PNG
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 6.90n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 60 mins followed by substrate addition b...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083673
PNG
(CHEMBL3422943)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C25H27N3O4/c1-2-31-24(29)22-17-23(28(27-22)20-13-7-4-8-14-20)18-10-9-15-21(16-18)32-25(30)26-19-11-5-3-6-12-19/h4,7-10,13-17,19H,2-3,5-6,11-12H2,1H3,(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50414921
PNG
(CHEMBL570812)
Show SMILES COc1nn(-c2ccc(NC(=O)OCc3ccccc3)c(C)c2)c(=O)o1
Show InChI InChI=1S/C18H17N3O5/c1-12-10-14(21-18(23)26-17(20-21)24-2)8-9-15(12)19-16(22)25-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3,(H,19,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 0 min followed by substrate addition by ...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM26739
PNG
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 30 mins followed by substrate addition b...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50414921
PNG
(CHEMBL570812)
Show SMILES COc1nn(-c2ccc(NC(=O)OCc3ccccc3)c(C)c2)c(=O)o1
Show InChI InChI=1S/C18H17N3O5/c1-12-10-14(21-18(23)26-17(20-21)24-2)8-9-15(12)19-16(22)25-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3,(H,19,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083674
PNG
(CHEMBL3422944)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 0 min followed by substrate addition by ...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083674
PNG
(CHEMBL3422944)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083674
PNG
(CHEMBL3422944)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 30 mins followed by substrate addition b...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083713
PNG
(CHEMBL3423130)
Show SMILES COC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C24H25N3O4/c1-30-23(28)21-16-22(27(26-21)19-12-6-3-7-13-19)17-9-8-14-20(15-17)31-24(29)25-18-10-4-2-5-11-18/h3,6-9,12-16,18H,2,4-5,10-11H2,1H3,(H,25,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083674
PNG
(CHEMBL3422944)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 60 mins followed by substrate addition b...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083714
PNG
(CHEMBL3423131)
Show SMILES CCCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H29N3O4/c1-2-16-32-25(30)23-18-24(29(28-23)21-13-7-4-8-14-21)19-10-9-15-22(17-19)33-26(31)27-20-11-5-3-6-12-20/h4,7-10,13-15,17-18,20H,2-3,5-6,11-12,16H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083676
PNG
(CHEMBL3422946)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C26H29N3O4/c1-3-32-25(30)23-17-24(29(28-23)21-14-12-18(2)13-15-21)19-8-7-11-22(16-19)33-26(31)27-20-9-5-4-6-10-20/h7-8,11-17,20H,3-6,9-10H2,1-2H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 29n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM26739
PNG
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 58n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 0 min followed by substrate addition by ...


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM26739
PNG
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 59n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083687
PNG
(CHEMBL3423104)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(Cc2ccccc2)n1
Show InChI InChI=1S/C26H29N3O4/c1-2-32-25(30)23-17-24(29(28-23)18-19-10-5-3-6-11-19)20-12-9-15-22(16-20)33-26(31)27-21-13-7-4-8-14-21/h3,5-6,9-12,15-17,21H,2,4,7-8,13-14,18H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083699
PNG
(CHEMBL3423116)
Show SMILES NC(=O)c1cc(-c2ccc(OC(=O)NC3CCCCC3)cc2)n(n1)-c1ccccc1
Show InChI InChI=1S/C23H24N4O3/c24-22(28)20-15-21(27(26-20)18-9-5-2-6-10-18)16-11-13-19(14-12-16)30-23(29)25-17-7-3-1-4-8-17/h2,5-6,9-15,17H,1,3-4,7-8H2,(H2,24,28)(H,25,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 71n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083685
PNG
(CHEMBL3423102)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C25H26N4O6/c1-2-34-24(30)22-16-23(28(27-22)19-11-13-20(14-12-19)29(32)33)17-7-6-10-21(15-17)35-25(31)26-18-8-4-3-5-9-18/h6-7,10-16,18H,2-5,8-9H2,1H3,(H,26,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 78n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083688
PNG
(CHEMBL3423105)
Show SMILES CCOC(=O)c1cc(-c2ccc(OC(=O)NC3CCCCC3)cc2)n(C)n1
Show InChI InChI=1S/C20H25N3O4/c1-3-26-19(24)17-13-18(23(2)22-17)14-9-11-16(12-10-14)27-20(25)21-15-7-5-4-6-8-15/h9-13,15H,3-8H2,1-2H3,(H,21,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 81n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083711
PNG
(CHEMBL3423128)
Show SMILES CCCCCCNC(=O)Oc1cccc(c1)-c1cc(nn1-c1ccccc1)C(=O)OCC
Show InChI InChI=1S/C25H29N3O4/c1-3-5-6-10-16-26-25(30)32-21-15-11-12-19(17-21)23-18-22(24(29)31-4-2)27-28(23)20-13-8-7-9-14-20/h7-9,11-15,17-18H,3-6,10,16H2,1-2H3,(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 88n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083715
PNG
(CHEMBL3423132)
Show SMILES CCCCCCNC(=O)Oc1cccc(c1)-c1cc(nn1-c1ccccc1)C(=O)OCCC
Show InChI InChI=1S/C26H31N3O4/c1-3-5-6-10-16-27-26(31)33-22-15-11-12-20(18-22)24-19-23(25(30)32-17-4-2)28-29(24)21-13-8-7-9-14-21/h7-9,11-15,18-19H,3-6,10,16-17H2,1-2H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 101n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083635
PNG
(CHEMBL3422942)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(CC)n1
Show InChI InChI=1S/C21H27N3O4/c1-3-24-19(14-18(23-24)20(25)27-4-2)15-9-8-12-17(13-15)28-21(26)22-16-10-6-5-7-11-16/h8-9,12-14,16H,3-7,10-11H2,1-2H3,(H,22,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 101n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083675
PNG
(CHEMBL3422945)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(OC)cc1
Show InChI InChI=1S/C26H29N3O5/c1-3-33-25(30)23-17-24(29(28-23)20-12-14-21(32-2)15-13-20)18-8-7-11-22(16-18)34-26(31)27-19-9-5-4-6-10-19/h7-8,11-17,19H,3-6,9-10H2,1-2H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 103n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083686
PNG
(CHEMBL3423103)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C25H25Cl2N3O4/c1-2-33-24(31)21-15-23(30(29-21)22-12-11-17(26)14-20(22)27)16-7-6-10-19(13-16)34-25(32)28-18-8-4-3-5-9-18/h6-7,10-15,18H,2-5,8-9H2,1H3,(H,28,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 123n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083677
PNG
(CHEMBL3423101)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C26H26F3N3O4/c1-2-35-24(33)22-16-23(32(31-22)20-13-11-18(12-14-20)26(27,28)29)17-7-6-10-21(15-17)36-25(34)30-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,30,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 132n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083710
PNG
(CHEMBL3423127)
Show SMILES CCOC(=O)c1cc(nn1-c1ccc(OC)cc1)-c1ccc(OC(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C26H29N3O5/c1-3-33-25(30)24-17-23(28-29(24)20-11-15-21(32-2)16-12-20)18-9-13-22(14-10-18)34-26(31)27-19-7-5-4-6-8-19/h9-17,19H,3-8H2,1-2H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 159n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083692
PNG
(CHEMBL3423109)
Show SMILES NC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C23H24N4O3/c24-22(28)20-15-21(27(26-20)18-11-5-2-6-12-18)16-8-7-13-19(14-16)30-23(29)25-17-9-3-1-4-10-17/h2,5-8,11-15,17H,1,3-4,9-10H2,(H2,24,28)(H,25,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 169n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083700
PNG
(CHEMBL3423117)
Show SMILES NC(=O)c1cc(-c2ccc(OC(=O)NC3CCCCC3)cc2)n(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H23ClN4O3/c24-16-8-10-18(11-9-16)28-21(14-20(27-28)22(25)29)15-6-12-19(13-7-15)31-23(30)26-17-4-2-1-3-5-17/h6-14,17H,1-5H2,(H2,25,29)(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 172n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083693
PNG
(CHEMBL3423110)
Show SMILES NC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H23ClN4O3/c24-16-9-11-18(12-10-16)28-21(14-20(27-28)22(25)29)15-5-4-8-19(13-15)31-23(30)26-17-6-2-1-3-7-17/h4-5,8-14,17H,1-3,6-7H2,(H2,25,29)(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 174n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083698
PNG
(CHEMBL3423115)
Show SMILES Cn1nc(cc1-c1ccc(OC(=O)NC2CCCCC2)cc1)C(N)=O
Show InChI InChI=1S/C18H22N4O3/c1-22-16(11-15(21-22)17(19)23)12-7-9-14(10-8-12)25-18(24)20-13-5-3-2-4-6-13/h7-11,13H,2-6H2,1H3,(H2,19,23)(H,20,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 209n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083689
PNG
(CHEMBL3423106)
Show SMILES CCOC(=O)c1cc(-c2ccc(OC(=O)NC3CCCCC3)cc2)n(CC)n1
Show InChI InChI=1S/C21H27N3O4/c1-3-24-19(14-18(23-24)20(25)27-4-2)15-10-12-17(13-11-15)28-21(26)22-16-8-6-5-7-9-16/h10-14,16H,3-9H2,1-2H3,(H,22,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 214n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083701
PNG
(CHEMBL3423118)
Show SMILES CCOC(=O)c1cc(nn1C)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H25N3O4/c1-3-26-19(24)18-13-17(22-23(18)2)14-8-7-11-16(12-14)27-20(25)21-15-9-5-4-6-10-15/h7-8,11-13,15H,3-6,9-10H2,1-2H3,(H,21,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 227n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083695
PNG
(CHEMBL3423112)
Show SMILES CC(C)NC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H30N4O3/c1-18(2)27-25(31)23-17-24(30(29-23)21-13-7-4-8-14-21)19-10-9-15-22(16-19)33-26(32)28-20-11-5-3-6-12-20/h4,7-10,13-18,20H,3,5-6,11-12H2,1-2H3,(H,27,31)(H,28,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 232n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083690
PNG
(CHEMBL3423107)
Show SMILES CCOC(=O)c1cc(-c2ccc(OC(=O)NC3CCCCC3)cc2)n(n1)-c1ccccc1
Show InChI InChI=1S/C25H27N3O4/c1-2-31-24(29)22-17-23(28(27-22)20-11-7-4-8-12-20)18-13-15-21(16-14-18)32-25(30)26-19-9-5-3-6-10-19/h4,7-8,11-17,19H,2-3,5-6,9-10H2,1H3,(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 268n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083691
PNG
(CHEMBL3423108)
Show SMILES CCOC(=O)c1cc(-c2ccc(OC(=O)NC3CCCCC3)cc2)n(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-12-10-18(26)11-13-20)17-8-14-21(15-9-17)33-25(31)27-19-6-4-3-5-7-19/h8-16,19H,2-7H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 281n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083696
PNG
(CHEMBL3423113)
Show SMILES O=C(NC1CCCCC1)Oc1cccc(c1)-c1cc(nn1-c1ccccc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C29H34N4O3/c34-28(30-22-12-4-1-5-13-22)26-20-27(33(32-26)24-16-8-3-9-17-24)21-11-10-18-25(19-21)36-29(35)31-23-14-6-2-7-15-23/h3,8-11,16-20,22-23H,1-2,4-7,12-15H2,(H,30,34)(H,31,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 288n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083634
PNG
(CHEMBL3422941)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(C)n1
Show InChI InChI=1S/C20H25N3O4/c1-3-26-19(24)17-13-18(23(2)22-17)14-8-7-11-16(12-14)27-20(25)21-15-9-5-4-6-10-15/h7-8,11-13,15H,3-6,9-10H2,1-2H3,(H,21,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 303n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083706
PNG
(CHEMBL3423123)
Show SMILES CCOC(=O)c1cc(nn1C)-c1ccc(OC(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C20H25N3O4/c1-3-26-19(24)18-13-17(22-23(18)2)14-9-11-16(12-10-14)27-20(25)21-15-7-5-4-6-8-15/h9-13,15H,3-8H2,1-2H3,(H,21,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 316n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083704
PNG
(CHEMBL3423121)
Show SMILES CCOC(=O)c1cc(nn1-c1ccc(Cl)cc1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)23-16-22(28-29(23)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 353n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083705
PNG
(CHEMBL3423122)
Show SMILES CCOC(=O)c1cc(nn1-c1ccc(OC)cc1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C26H29N3O5/c1-3-33-25(30)24-17-23(28-29(24)20-12-14-21(32-2)15-13-20)18-8-7-11-22(16-18)34-26(31)27-19-9-5-4-6-10-19/h7-8,11-17,19H,3-6,9-10H2,1-2H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 407n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083697
PNG
(CHEMBL3423114)
Show SMILES CCN(CC)C(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C27H32N4O3/c1-3-30(4-2)26(32)24-19-25(31(29-24)22-15-9-6-10-16-22)20-12-11-17-23(18-20)34-27(33)28-21-13-7-5-8-14-21/h6,9-12,15-19,21H,3-5,7-8,13-14H2,1-2H3,(H,28,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 448n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083716
PNG
(CHEMBL3423133)
Show SMILES OCc1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C23H25N3O3/c27-16-19-15-22(26(25-19)20-11-5-2-6-12-20)17-8-7-13-21(14-17)29-23(28)24-18-9-3-1-4-10-18/h2,5-8,11-15,18,27H,1,3-4,9-10,16H2,(H,24,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 462n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083702
PNG
(CHEMBL3423119)
Show SMILES CCOC(=O)c1cc(nn1CC)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C21H27N3O4/c1-3-24-19(20(25)27-4-2)14-18(23-24)15-9-8-12-17(13-15)28-21(26)22-16-10-6-5-7-11-16/h8-9,12-14,16H,3-7,10-11H2,1-2H3,(H,22,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 507n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083703
PNG
(CHEMBL3423120)
Show SMILES CCOC(=O)c1cc(nn1-c1ccccc1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C25H27N3O4/c1-2-31-24(29)23-17-22(27-28(23)20-13-7-4-8-14-20)18-10-9-15-21(16-18)32-25(30)26-19-11-5-3-6-12-19/h4,7-10,13-17,19H,2-3,5-6,11-12H2,1H3,(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 539n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083709
PNG
(CHEMBL3423126)
Show SMILES CCOC(=O)c1cc(nn1-c1ccc(Cl)cc1)-c1ccc(OC(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)23-16-22(28-29(23)20-12-10-18(26)11-13-20)17-8-14-21(15-9-17)33-25(31)27-19-6-4-3-5-7-19/h8-16,19H,2-7H2,1H3,(H,27,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 586n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083708
PNG
(CHEMBL3423125)
Show SMILES CCOC(=O)c1cc(nn1-c1ccccc1)-c1ccc(OC(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C25H27N3O4/c1-2-31-24(29)23-17-22(27-28(23)20-11-7-4-8-12-20)18-13-15-21(16-14-18)32-25(30)26-19-9-5-3-6-10-19/h4,7-8,11-17,19H,2-3,5-6,9-10H2,1H3,(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 592n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083707
PNG
(CHEMBL3423124)
Show SMILES CCOC(=O)c1cc(nn1CC)-c1ccc(OC(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C21H27N3O4/c1-3-24-19(20(25)27-4-2)14-18(23-24)15-10-12-17(13-11-15)28-21(26)22-16-8-6-5-7-9-16/h10-14,16H,3-9H2,1-2H3,(H,22,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 603n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083694
PNG
(CHEMBL3423111)
Show SMILES COc1ccc(cc1)-n1nc(cc1-c1cccc(OC(=O)NC2CCCCC2)c1)C(N)=O
Show InChI InChI=1S/C24H26N4O4/c1-31-19-12-10-18(11-13-19)28-22(15-21(27-28)23(25)29)16-6-5-9-20(14-16)32-24(30)26-17-7-3-2-4-8-17/h5-6,9-15,17H,2-4,7-8H2,1H3,(H2,25,29)(H,26,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 743n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (FAAH)


(Homo sapiens (Human))
BDBM50083712
PNG
(CHEMBL3423129)
Show SMILES OC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C23H23N3O4/c27-22(28)20-15-21(26(25-20)18-11-5-2-6-12-18)16-8-7-13-19(14-16)30-23(29)24-17-9-3-1-4-10-17/h2,5-8,11-15,17H,1,3-4,9-10H2,(H,24,29)(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.27E+3n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Homo sapiens (human))
BDBM50083673
PNG
(CHEMBL3422943)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C25H27N3O4/c1-2-31-24(29)22-17-23(28(27-22)20-13-7-4-8-14-20)18-10-9-15-21(16-18)32-25(30)26-19-11-5-3-6-12-19/h4,7-10,13-17,19H,2-3,5-6,11-12H2,1H3,(H,26,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 mins


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Homo sapiens (human))
BDBM50083676
PNG
(CHEMBL3422946)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C26H29N3O4/c1-3-32-25(30)23-17-24(29(28-23)21-14-12-18(2)13-15-21)19-8-7-11-22(16-19)33-26(31)27-20-9-5-4-6-10-20/h7-8,11-17,20H,3-6,9-10H2,1-2H3,(H,27,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.40E+4n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 mins


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Homo sapiens (human))
BDBM50083714
PNG
(CHEMBL3423131)
Show SMILES CCCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H29N3O4/c1-2-16-32-25(30)23-18-24(29(28-23)21-13-7-4-8-14-21)19-10-9-15-22(17-19)33-26(31)27-20-11-5-3-6-12-20/h4,7-10,13-15,17-18,20H,2-3,5-6,11-12,16H2,1H3,(H,27,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 mins


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Homo sapiens (human))
BDBM50083713
PNG
(CHEMBL3423130)
Show SMILES COC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C24H25N3O4/c1-30-23(28)21-16-22(27(26-21)19-12-6-3-7-13-19)17-9-8-14-20(15-17)31-24(29)25-18-10-4-2-5-11-18/h3,6-9,12-16,18H,2,4-5,10-11H2,1H3,(H,25,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 mins


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Homo sapiens (human))
BDBM50083674
PNG
(CHEMBL3422944)
Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.30E+4n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 mins


Eur J Med Chem 97: 289-305 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.064
BindingDB Entry DOI: 10.7270/Q29S1SR3
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%