Compile Data Set for Download or QSAR
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Found 100 Enz. Inhib. hit(s) with all data for entry = 50046397
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109578(CHEMBL3604156)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109729(CHEMBL3604185)
Affinity DataIC50:  2nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109751(CHEMBL3604184)
Affinity DataIC50:  4nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109578(CHEMBL3604156)
Affinity DataIC50:  10nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109746(CHEMBL3604180)
Affinity DataIC50:  13nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109814(CHEMBL3604153)
Affinity DataIC50:  14nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109746(CHEMBL3604180)
Affinity DataIC50:  20nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109813(CHEMBL3604152)
Affinity DataIC50:  22nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109568(CHEMBL3604132)
Affinity DataIC50:  24nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109539(CHEMBL3604138)
Affinity DataIC50:  26nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109643(CHEMBL3604158)
Affinity DataIC50:  27nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109814(CHEMBL3604153)
Affinity DataIC50:  32nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109730(CHEMBL3604151)
Affinity DataIC50:  33nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109729(CHEMBL3604185)
Affinity DataIC50:  34nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109649(CHEMBL3604162)
Affinity DataIC50:  37nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109752(CHEMBL3604164)
Affinity DataIC50:  39nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109577(CHEMBL3604155)
Affinity DataIC50:  39nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109736(CHEMBL3604149)
Affinity DataIC50:  42nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109576(CHEMBL3604154)
Affinity DataIC50:  42nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109539(CHEMBL3604138)
Affinity DataIC50:  43nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109707(CHEMBL445420)
Affinity DataIC50:  47nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  56nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109740(CHEMBL3604173)
Affinity DataIC50:  68nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109731(CHEMBL3604166)
Affinity DataIC50:  69nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109813(CHEMBL3604152)
Affinity DataIC50:  71nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  78nMAssay Description:Inhibition of pig 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arach...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109741(CHEMBL3604175)
Affinity DataIC50:  79nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109568(CHEMBL3604132)
Affinity DataIC50:  81nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109730(CHEMBL3604151)
Affinity DataIC50:  85nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109562(CHEMBL3604141)
Affinity DataIC50:  92nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109570(CHEMBL3604134)
Affinity DataIC50:  94nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109737(CHEMBL3604170)
Affinity DataIC50:  97nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50:  99nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109646(CHEMBL3604160)
Affinity DataIC50:  112nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109645(CHEMBL3604159)
Affinity DataIC50:  117nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109815(CHEMBL3604137)
Affinity DataIC50:  118nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109747(CHEMBL3604181)
Affinity DataIC50:  124nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109561(CHEMBL3604139)
Affinity DataIC50:  130nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109751(CHEMBL3604184)
Affinity DataIC50:  131nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109643(CHEMBL3604158)
Affinity DataIC50:  150nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109570(CHEMBL3604134)
Affinity DataIC50:  168nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109562(CHEMBL3604141)
Affinity DataIC50:  180nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109567(CHEMBL3604131)
Affinity DataIC50:  180nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109733(CHEMBL3604146)
Affinity DataIC50:  183nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109642(CHEMBL3604157)
Affinity DataIC50:  184nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109700(CHEMBL3604163)
Affinity DataIC50:  216nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109565(CHEMBL3604130)
Affinity DataIC50:  270nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109648(CHEMBL3604161)
Affinity DataIC50:  279nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109577(CHEMBL3604155)
Affinity DataIC50:  290nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109812(CHEMBL3604140)
Affinity DataIC50:  334nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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