Affinity DataIC50: 0.700nMAssay Description:Binding affinity to His-tagged BRD4 bromodomain1 (unknown origin) incubated for 1 hr in presence of Europium Cryptate-labeled streptavidin by TR-FRET...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to His-tagged BRD4 bromodomain1 (unknown origin) (57 to 168 residues) incubated for 1 hr in presence of Europium Cryptate-labeled st...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to His-tagged BRD4 bromodomain1 (unknown origin) incubated for 1 hr in presence of Europium Cryptate-labeled streptavidin by TR-FRET...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 (57 to 168 residues) incubated for 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 60 mins by Alphascreen assa...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 (1 to 477 residues) expressed in Escherichia coli in...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 60 mins by Alphascreen assa...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from His/Flag-tagged BRD4 bromodomain1 (42 to 168 residues) (unknown origin) incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: <14nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 60 mins by Alphascreen assa...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <20nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (67 to 152 residues) (unknown origin) incubated for 1 hr a...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 1 hr at 22 degC followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 1 hr at 22 degC followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from His-tagged BRD4 bromodomain1 (42 to 168 residues) (unknown origin) incubated for 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Binding affinity to His-tagged BRD4 bromodomain1 (unknown origin) (57 to 168 residues) incubated for 1 hr in presence of Europium Cryptate-labeled st...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Binding affinity to CERC2 (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 (44 to 168 residues) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged CBP by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Binding affinity to His-tagged BRD4 bromodomain1 (unknown origin) incubated for 1 hr in presence of Europium Cryptate-labeled streptavidin by TR-FRET...More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (44 to 477 residues) (unknown origin) incubated for 35 min...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 after 20 mins by Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 after 75 mins by Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 (44 to 168 residues) (unknown origin) after 60 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <150nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of CBP (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: <200nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: <200nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 after 75 mins by Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 60 mins by Alphascreen assa...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged BRD4 bromodomain1 europium chelate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 323nMAssay Description:Inhibition of CBP (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from His/Flag-tagged BRD4 bromodomain1 (42 to 168 residues) (unknown origin) incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from his-tagged BRD4 bromodomain1 (unknown origin) incubated for 60 mins by Alphascreen assa...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of FITC-labeled MS417 from BRD4 bromodomain 1 (unknown origin) after 1 hr by fluorescence anisotropyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of doxorubicin-stimulated p53 (unknown origin) expressed in human RKO cells preincubated for 24 hrs followed by addition of doxorubicin fo...More data for this Ligand-Target Pair
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of CBP (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity to human CBP by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.96E+4nMAssay Description:Binding affinity to CBP bromodomain (unknown origin) by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
TargetBromodomain and PHD finger-containing protein 3(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKd: 410nMAssay Description:Binding affinity to BRPF3 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 151nMAssay Description:Binding affinity to CBP (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to BRPF1B (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:Binding affinity to CERC2 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 99nMAssay Description:Binding affinity to BRD9 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Binding affinity to BRPF2 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to BRPF1B (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to BRPF2 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 390nMAssay Description:Binding affinity to CBP (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to BRD9 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair