Compile Data Set for Download or QSAR
maximum 50k data
Found 68 Enz. Inhib. hit(s) with all data for entry = 50046876
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  2nMAssay Description:Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50134785(CHEMBL3753512)
Affinity DataIC50:  2nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  3nMAssay Description:Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  4nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50134786(CHEMBL3751904)
Affinity DataIC50:  5nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  6nMAssay Description:Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  10nMAssay Description:Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50388620(CHEMBL2058538)
Affinity DataIC50:  14nMAssay Description:Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50134785(CHEMBL3753512)
Affinity DataIC50:  14nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  21nMAssay Description:Inhibition of human Ret V804L mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human p70S6K by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136293(CHEMBL3752118)
Affinity DataIC50:  27nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136227(CHEMBL3753958)
Affinity DataIC50:  41nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136224(CHEMBL3752395)
Affinity DataIC50:  41nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50134786(CHEMBL3751904)
Affinity DataIC50:  41nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136294(CHEMBL3752879)
Affinity DataIC50:  52nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50388620(CHEMBL2058538)
Affinity DataIC50:  54nMAssay Description:Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50388620(CHEMBL2058538)
Affinity DataIC50:  57nMAssay Description:Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human FGR by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136229(CHEMBL3752712)
Affinity DataIC50:  68nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  72nMAssay Description:Inhibition of recombinant human FLT4 by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136235(CHEMBL3754346)
Affinity DataIC50:  74nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50388620(CHEMBL2058538)
Affinity DataIC50:  75nMAssay Description:Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  82nMAssay Description:Inhibition of recombinant human MEK2 by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  96nMAssay Description:Inhibition of recombinant human VGFR2 by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136232(CHEMBL3753242)
Affinity DataIC50:  96nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  137nMAssay Description:Inhibition of recombinant human HCK by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  142nMAssay Description:Inhibition of recombinant human MEK1 by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136236(CHEMBL3754092)
Affinity DataIC50:  150nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136293(CHEMBL3752118)
Affinity DataIC50:  182nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136295(CHEMBL3754442)
Affinity DataIC50:  190nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136223(CHEMBL3751965)
Affinity DataIC50:  210nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136290(CHEMBL3752025)
Affinity DataIC50:  213nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136229(CHEMBL3752712)
Affinity DataIC50:  217nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human Ret V804L mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50134789(CHEMBL3753714)
Affinity DataIC50:  241nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136225(CHEMBL3753903)
Affinity DataIC50:  241nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136226(CHEMBL3753341)
Affinity DataIC50:  311nMAssay Description:Inhibition of recombinant human RSK1 by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136294(CHEMBL3752879)
Affinity DataIC50:  354nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136224(CHEMBL3752395)
Affinity DataIC50:  355nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  358nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136227(CHEMBL3753958)
Affinity DataIC50:  531nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136235(CHEMBL3754346)
Affinity DataIC50:  557nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50134788(CHEMBL3752736)
Affinity DataIC50:  583nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136290(CHEMBL3752025)
Affinity DataIC50:  903nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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