TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataKi: 64nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant MMP13 (85 to 255 residues) expressed in Escherichia coli using 5-FAM/QXLTM as substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK as substrate after 40 mins by scintillation counting method in presence of [gamma-33P-ATP]More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]-17beta-estradiol from human recombinant ERalpha expressed in rabbit reticulocytesMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of inactivated PLK1 in human HeLa cells using casein as substrate by immunoprecipitation assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D2(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant CDK4/Cyclin D2 expressed in baculovirus infected insect Sf9 cells using G1 peptide as substrate after 45 mins by Top ...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Displacement of [3H]-17beta-estradiol from human recombinant ERbeta expressed in rabbit reticulocytesMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataEC50: 6.00E+3nMAssay Description:Activation of human liver cathepsin L using Z-FR-AMC as substrate measured for 120 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Swiss Federal Institute Of Technology (Eth)
Curated by ChEMBL
Affinity DataEC50: 6.00E+3nMAssay Description:Inhibition of human recombinant PDE3B expressed in insect Sf9 cells assessed as residual cAMP level after 30 mins by HTRF assayMore data for this Ligand-Target Pair