BindingDB PrimarySearch

Found 54 Enz. Inhib. hit(s) with all data for entry = 50010200

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)

IC50: 0.200nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536008(CHEMBL4550647)

IC50: 1.60nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536019(CHEMBL4516233)

IC50: 3.20nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.20nMAssay Description:Inhibition of FLT3 (unknown origin) (592 to 969 residues)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536015(CHEMBL4589511)

IC50: 5.20nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536010(CHEMBL4572416)

IC50: 6.10nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536014(CHEMBL4579991)

IC50: 8.20nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536006(CHEMBL4593900)

IC50: 8.70nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536018(CHEMBL4578522)

IC50: 22nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536016(CHEMBL4591095)

IC50: 28nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195081(US9670213, Compound 001 8-(4-aminophenyl)-2-(4-met...)

IC50: 29nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536012(CHEMBL4546400)

IC50: 32nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195860(US9670213, Compound 005 8-(3-aminophenyl)-2-(4-met...)

IC50: 34nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536005(CHEMBL4573506)

IC50: 36nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536013(CHEMBL4557216)

IC50: 37nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195874(US9670213, Compound 019 N-(4-(2-(4-(4-methyl-1-pip...)

IC50: 47nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195857(US9670213, Compound 002 N-(4-(2-(4-methoxyphenylam...)

IC50: 108nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536011(CHEMBL4522949)

IC50: 127nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195886(US9670213, Compound 031 N-(4-(2-(2-methoxy)-4-(4-m...)

IC50: 153nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195869(US9670213, Compound 014 N-(4-(7-oxo-2-(phenylamino...)

IC50: 165nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195858(US9670213, Compound 003 N-(4-(2-(4-morpholino-phen...)

IC50: 173nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195864(US9670213, Compound 009 4-(dimethylamino)-N-(4-(2-...)

IC50: 184nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)

IC50: 220nMAssay Description:Inhibition of FLT3 (unknown origin) autophosphorylation by cell based enzyme-linked immunosorbent assayMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536007(CHEMBL4530420)

IC50: 255nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195875(US9670213, Compound 020 N-(3-(2-(4-(4-methyl-1-pip...)

IC50: 312nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536017(CHEMBL4565143)

IC50: 347nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195871(US9670213, Compound 016 N-(4-(2-(4-chlorophenylami...)

IC50: 384nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195878(US9670213, Compound 023 N-(3-(2-(4-(diethylamino)p...)

IC50: 1.06E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195873(US9670213, Compound 018 N-(3-(2-(4-morpholinopheny...)

IC50: 1.14E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195887(US9670213, Compound 032 N-(3-(2-(2-methoxy-4-(4-me...)

IC50: 1.32E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195877(US9670213, Compound 022 N-(3-(7-oxo-2-(4-(1-pyrrol...)

IC50: 1.53E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195876(US9670213, Compound 021 N-(3-(7-oxo-2-(4-(1-piperi...)

IC50: 1.75E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195861(US9670213, Compound 006 N-(3-(2-(4-methoxyphenylam...)

IC50: 1.87E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195870(US9670213, Compound 015 N-(3-(7-oxo-2-(phenylamino...)

IC50: 2.92E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536009(CHEMBL4570330)

IC50: 2.96E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195872(US9670213, Compound 017 N-(3-(2-(4-chlorophenylami...)

IC50: 3.59E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195865(US9670213, Compound 010 4-(dimethylamino)-N-(3-(2-...)

IC50: 4.41E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM195879(US9670213, Compound 024 N-(3-(2-(4-(acetylamino)-p...)

IC50: 5.45E+3nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 (564 to 993 residues) expressed in baculovirus expression system using peptide FAM-P2 as substrate inc...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.70nMAssay Description:Binding affinity to FLT3 D835H mutant (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536008(CHEMBL4550647)

Kd: 79nMAssay Description:Binding affinity to auto-inhibited human partial length wild type FLT3 (564 to 969 residues) expressed in mammalian expression system after 1 hrMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536008(CHEMBL4550647)

Kd: 5nMAssay Description:Binding affinity to human partial length wild type FLT3 (592 to 969 residues) expressed in bacterial expression system after 1 hrMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536008(CHEMBL4550647)

Kd: 6.90nMAssay Description:Binding affinity to human partial length FLT3 ITD mutant expressed in bacterial expression system after 1 hrMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536006(CHEMBL4593900)

Kd: 32nMAssay Description:Binding affinity to human partial length FLT3 D835Y mutant (580 to 969 residues) expressed in bacterial expression system after 1 hrMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.30nMAssay Description:Binding affinity to wild type FLT3 (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.10nMAssay Description:Binding affinity to FLT3 D835Y mutant (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536006(CHEMBL4593900)

Kd: 270nMAssay Description:Binding affinity to human partial length FLT3 ITD mutant expressed in bacterial expression system after 1 hrMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536006(CHEMBL4593900)

Kd: 75nMAssay Description:Binding affinity to human partial length wild type FLT3 (592 to 969 residues) expressed in bacterial expression system after 1 hrMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536006(CHEMBL4593900)

Kd: 44nMAssay Description:Binding affinity to human partial length FLT3 D835H mutant (592 to 969 residues) expressed in bacterial expression system after 1 hrMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50536008(CHEMBL4550647)

Kd: 1.80nMAssay Description:Binding affinity to human partial length FLT3 D835H mutant (592 to 969 residues) expressed in bacterial expression system after 1 hrMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 8.80nMAssay Description:Binding affinity to FLT3 ITD mutant (unknown origin)More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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