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PubMed code 27662031

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 3


(Homo sapiens (human))
BDBM50210628
PNG
(CHEMBL3946861)
Show SMILES CCSc1ncc(-c2cc([nH]c(=N)c2C#N)-c2ccc(Br)cc2)n1Cc1ccccc1
Show InChI InChI=1S/C24H20BrN5S/c1-2-31-24-28-14-22(30(24)15-16-6-4-3-5-7-16)19-12-21(29-23(27)20(19)13-26)17-8-10-18(25)11-9-17/h3-12,14H,2,15H2,1H3,(H2,27,29)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a



Hamdard University

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using fluorescein-labelled cAMP as substrate measured after 60 mins by IMAP TR-FRET assay


Eur J Med Chem 125: 143-189 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.023
BindingDB Entry DOI: 10.7270/Q23T9K6Z
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%