TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human FGFR1 in presence of ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Inhibition of recombinant human Lyn using peptide substrate poly[Glu:Tyr] (4:1) in presence of [33-P]ATP by kinase hotspot assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 0.370nMAssay Description:Inhibition of recombinant human ABL using peptide substrate EAIYAAPFAKKK in presence of [33-P]ATP by kinase hotspot assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged c-KIT (544 to 976 residues) expressed in baculovirus infected sf9 cells using biotinylated...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant PDGFRbeta (unknown origin) expressed in baculovirus infected insect cells using biotinylated peptide substrate GGLFDDPSYVNV...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using peptidic substrates in presence of ATP by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using peptidic substrates in presence of ATP by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant GST fused FGFR3 (unknown origin) using poly(EY) 4:1 as substrate in presence of [gamma-32P]ATP after 10 mins by scintillati...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF-1R (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged FLT3 (571 to 993 residues) expressed in baculovirus infected sf9 cells using biotinylated ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human VEGFR2 using substrate poly[Glu:Tyr] (4:1) in presence of [33-P]ATP by kinase hotspot assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human FGFR3 in presence of ATPMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human FGFR1 using substrate KKKSPGEYVNIEFG in presence of [33-P]ATP by kinase hotspot assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human FGFR2 in presence of ATPMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR4 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus expression system using CSKtide...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant VEGFR3 (unknown origin) expressed in baculovirus infected insect cells using biotinylated peptide substrate GGGGQDGKDYIVLPI...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) expressed in baculovirus infected insect cells using biotinylated peptide substrate GGGGQDGKDYIVLPI ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant FGFR3 (unknown origin) using biotinylated peptide substrate GGGGQDGKDYIVLPI in presence of ATP incubated for 1 to 4 hrs by ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant VEGFR1 (unknown origin) expressed in baculovirus infected insect cells using biotinylated peptide substrate GGGGQDGKDYIVLPI...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) expressed in baculovirus infected insect cells using biotinylated peptide substrate GGGGQDGKDYIVLPI...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant full length human FGFR1 expressed in baculovirus infected insect cells in presence of [gamma-32P]ATP after 10 mins by scint...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant FGFR4 (unknown origin) using peptidic substrates in presence of ATP by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR3 cytoplasmic domain (436 to 806 end residues) expressed in baculovirus expression system using CSKtide...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 165nMAssay Description:Inhibition of recombinant human FGFR4 in presence of ATPMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 493nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR2 cytoplasmic domain (399 to 821 end residues) expressed in baculovirus expression system using CSKtide...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 591nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR1 cytoplasmic domain (398 to 822 residues) expressed in baculovirus expression system using CSKtide as ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant His6-tagged FGFR1 (unknown origin) expressed in Escherichia coli BL21(DE3)-RILP using peptidic substrate by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 938nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR4 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus expression system using CSKtide...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant His6-tagged FGFR2 (unknown origin) expressed in Escherichia coli BL21(DE3)-RILP using peptidic substrate by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
The First Affiliated Hospital Of Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair