BindingDB logo
myBDB logout

PubMed code 27933897

Compile data set for download or QSAR
Found 18 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232848
PNG
(CHEMBL4084310)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)NCCCc4cc(c(O)c(c4)C(C)(C)C)C(C)(C)C)C(=O)C3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C35H43NO7/c1-17-28(39)26(19(3)37)31-27(29(17)40)35(10)24(43-31)16-23(38)25(32(35)42)18(2)36-13-11-12-20-14-21(33(4,5)6)30(41)22(15-20)34(7,8)9/h14-16,36,39-41H,11-13H2,1-10H3/b25-18+
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 160n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232847
PNG
(CHEMBL4090202)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)NCCc4cc(c(O)c(c4)C(C)(C)C)C(C)(C)C)C(=O)C3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C34H41NO7/c1-16-27(38)25(18(3)36)30-26(28(16)39)34(10)23(42-30)15-22(37)24(31(34)41)17(2)35-12-11-19-13-20(32(4,5)6)29(40)21(14-19)33(7,8)9/h13-15,35,38-40H,11-12H2,1-10H3/b24-17+
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232843
PNG
(CHEMBL2207624)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccc(Br)cc4)C(=O)[C@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20BrNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-13(25)6-8-14/h5-9,26,29-30H,1-4H3/b17-11+/t24-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232845
PNG
(CHEMBL2207625)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccc(Br)cc4)C(=O)[C@@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20BrNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-13(25)6-8-14/h5-9,26,29-30H,1-4H3/b17-11+/t24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 570n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232846
PNG
(CHEMBL4069136)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4cccc(Br)c4)C(=O)C3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20BrNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-6-13(25)8-14/h5-9,26,29-30H,1-4H3/b17-11+
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
MMDB
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 750n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232849
PNG
(CHEMBL4102274)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)NCCc4ccc(O)cc4)C(=O)[C@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C26H25NO7/c1-12-22(31)20(14(3)28)24-21(23(12)32)26(4)18(34-24)11-17(30)19(25(26)33)13(2)27-10-9-15-5-7-16(29)8-6-15/h5-8,11,27,29,31-32H,9-10H2,1-4H3/b19-13+/t26-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 790n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232836
PNG
(CHEMBL2207621)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccc(F)cc4)C(=O)[C@@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20FNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-13(25)6-8-14/h5-9,26,29-30H,1-4H3/b17-11+/t24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 940n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232838
PNG
(CHEMBL4068083)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4cccc(F)c4)C(=O)C3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20FNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-6-13(25)8-14/h5-9,26,29-30H,1-4H3/b17-11+
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.39E+3n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232850
PNG
(CHEMBL4069754)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccccc4)C(=O)[C@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H21NO6/c1-11-20(28)18(13(3)26)22-19(21(11)29)24(4)16(31-22)10-15(27)17(23(24)30)12(2)25-14-8-6-5-7-9-14/h5-10,25,28-29H,1-4H3/b17-12+/t24-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.53E+3n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232837
PNG
(CHEMBL2207620)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccc(F)cc4)C(=O)[C@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20FNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-13(25)6-8-14/h5-9,26,29-30H,1-4H3/b17-11+/t24-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.54E+3n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232851
PNG
(CHEMBL2207623)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccc(Cl)cc4)C(=O)[C@@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20ClNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-13(25)6-8-14/h5-9,26,29-30H,1-4H3/b17-11+/t24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.62E+3n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232844
PNG
(CHEMBL2207622)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccc(Cl)cc4)C(=O)[C@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20ClNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-13(25)6-8-14/h5-9,26,29-30H,1-4H3/b17-11+/t24-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.81E+3n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232835
PNG
(CHEMBL4063265)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccccc4)C(=O)[C@@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H21NO6/c1-11-20(28)18(13(3)26)22-19(21(11)29)24(4)16(31-22)10-15(27)17(23(24)30)12(2)25-14-8-6-5-7-9-14/h5-10,25,28-29H,1-4H3/b17-12+/t24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.92E+3n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232843
PNG
(CHEMBL2207624)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)Nc4ccc(Br)cc4)C(=O)[C@]3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C24H20BrNO6/c1-10-20(29)18(12(3)27)22-19(21(10)30)24(4)16(32-22)9-15(28)17(23(24)31)11(2)26-14-7-5-13(25)6-8-14/h5-9,26,29-30H,1-4H3/b17-11+/t24-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) assessed as reduction in BHQ1 excision from 3'-end of [32P]-labeled oligonucleotide substrate after 2...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50056923
PNG
((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Show SMILES CC(=O)C1C(=O)C=C2Oc3c(c(O)c(C)c(O)c3C(C)=O)[C@@]2(C)C1=O
Show InChI InChI=1S/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5,11,22-23H,1-4H3/t11?,18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
Purchase

CHEBI
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232839
PNG
(CHEMBL4104897)
Show SMILES CN(C)CCN\C(C)=C1/C(=O)C=C2Oc3c(c(O)c(C)c(O)c3C(C)=O)C2(C)C1=O
Show InChI InChI=1S/C22H26N2O6/c1-10-18(27)16(12(3)25)20-17(19(10)28)22(4)14(30-20)9-13(26)15(21(22)29)11(2)23-7-8-24(5)6/h9,23,27-28H,7-8H2,1-6H3/b15-11+
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232841
PNG
((+)-Usnic Acid | (-)-USNIC ACID | (-)-Usnic Acid |...)
Show SMILES CC(=O)C1=C(O)C=C2Oc3c(c(O)c(C)c(O)c3C(C)=O)[C@]2(C)C1=O
Show InChI InChI=1S/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5,21-23H,1-4H3/t18-/m1/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))
BDBM50232840
PNG
(CHEMBL4087033)
Show SMILES CC(=O)c1c2OC3=CC(=O)\C(=C(\C)NCCCN4CCOCC4)C(=O)C3(C)c2c(O)c(C)c1O
Show InChI InChI=1S/C25H30N2O7/c1-13-21(30)19(15(3)28)23-20(22(13)31)25(4)17(34-23)12-16(29)18(24(25)32)14(2)26-6-5-7-27-8-10-33-11-9-27/h12,26,30-31H,5-11H2,1-4H3/b18-14+
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...


J Nat Prod 79: 2961-2967 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00979
BindingDB Entry DOI: 10.7270/Q20C4Z0H
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%