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PubMed code 28126287

Compile data set for download or QSAR
Found 50 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222161
PNG
(6,8-dibromo-2-(3-bromo-4-chloro-phenyl)-2-methyl-2...)
Show SMILES CC1(NC(=O)c2cc(Br)cc(Br)c2N1)c1ccc(Cl)c(Br)c1
Show InChI InChI=1S/C15H10Br3ClN2O/c1-15(7-2-3-12(19)10(17)4-7)20-13-9(14(22)21-15)5-8(16)6-11(13)18/h2-6,20H,1H3,(H,21,22)
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UniChem
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222163
PNG
(6,8-dibromo-2,2-bis(2-methylpropyl)-2,3-dihydroqui...)
Show SMILES CC(C)CC1(CC(C)C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C16H22Br2N2O/c1-9(2)7-16(8-10(3)4)19-14-12(15(21)20-16)5-11(17)6-13(14)18/h5-6,9-10,19H,7-8H2,1-4H3,(H,20,21)
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n/an/a 2.50E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222157
PNG
(6,8-dibromo-2-methyl-2-phenyl-2,3-dihydroquinazoli...)
Show SMILES CC1(NC(=O)c2cc(Br)cc(Br)c2N1)c1ccccc1
Show InChI InChI=1S/C15H12Br2N2O/c1-15(9-5-3-2-4-6-9)18-13-11(14(20)19-15)7-10(16)8-12(13)17/h2-8,18H,1H3,(H,19,20)
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n/an/a 3.50E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222161
PNG
(6,8-dibromo-2-(3-bromo-4-chloro-phenyl)-2-methyl-2...)
Show SMILES CC1(NC(=O)c2cc(Br)cc(Br)c2N1)c1ccc(Cl)c(Br)c1
Show InChI InChI=1S/C15H10Br3ClN2O/c1-15(7-2-3-12(19)10(17)4-7)20-13-9(14(22)21-15)5-8(16)6-11(13)18/h2-6,20H,1H3,(H,21,22)
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n/an/a 3.70E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222153
PNG
(2-methyl-2-(4-methylphenyl)-6,8-dinitro-1,2,3,4-te...)
Show SMILES Cc1ccc(cc1)C1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C16H14N4O5/c1-9-3-5-10(6-4-9)16(2)17-14-12(15(21)18-16)7-11(19(22)23)8-13(14)20(24)25/h3-8,17H,1-2H3,(H,18,21)
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n/an/a 3.80E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222155
PNG
(6,8-dinitro-2,2-bis(2-methylpropyl)-2,3-dihydroqui...)
Show SMILES CC(C)CC1(CC(C)C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C16H22N4O5/c1-9(2)7-16(8-10(3)4)17-14-12(15(21)18-16)5-11(19(22)23)6-13(14)20(24)25/h5-6,9-10,17H,7-8H2,1-4H3,(H,18,21)
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n/an/a 3.90E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM10404
PNG
((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Show SMILES COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24
Show InChI InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1
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PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222154
PNG
(6,8-dinitro-2-methyl-2-(2-methylpropyl)-2,3-dihydr...)
Show SMILES CC(C)CC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N4O5/c1-7(2)6-13(3)14-11-9(12(18)15-13)4-8(16(19)20)5-10(11)17(21)22/h4-5,7,14H,6H2,1-3H3,(H,15,18)
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n/an/a 4.60E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222155
PNG
(6,8-dinitro-2,2-bis(2-methylpropyl)-2,3-dihydroqui...)
Show SMILES CC(C)CC1(CC(C)C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C16H22N4O5/c1-9(2)7-16(8-10(3)4)17-14-12(15(21)18-16)5-11(19(22)23)6-13(14)20(24)25/h5-6,9-10,17H,7-8H2,1-4H3,(H,18,21)
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n/an/a 5.30E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222160
PNG
(6,8-dibromo-2-methyl-2-propyl-2,3-dihydroquinazoli...)
Show SMILES CCCC1(C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C12H14Br2N2O/c1-3-4-12(2)15-10-8(11(17)16-12)5-7(13)6-9(10)14/h5-6,15H,3-4H2,1-2H3,(H,16,17)
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n/an/a 5.40E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222149
PNG
(2-methyl-6,8-dinitro-2-(3-nitro-phenyl)-2,3-dihydr...)
Show SMILES CC1(NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C15H11N5O7/c1-15(8-3-2-4-9(5-8)18(22)23)16-13-11(14(21)17-15)6-10(19(24)25)7-12(13)20(26)27/h2-7,16H,1H3,(H,17,21)
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n/an/a 6.20E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222157
PNG
(6,8-dibromo-2-methyl-2-phenyl-2,3-dihydroquinazoli...)
Show SMILES CC1(NC(=O)c2cc(Br)cc(Br)c2N1)c1ccccc1
Show InChI InChI=1S/C15H12Br2N2O/c1-15(9-5-3-2-4-6-9)18-13-11(14(20)19-15)7-10(16)8-12(13)17/h2-8,18H,1H3,(H,19,20)
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n/an/a 6.40E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222149
PNG
(2-methyl-6,8-dinitro-2-(3-nitro-phenyl)-2,3-dihydr...)
Show SMILES CC1(NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C15H11N5O7/c1-15(8-3-2-4-9(5-8)18(22)23)16-13-11(14(21)17-15)6-10(19(24)25)7-12(13)20(26)27/h2-7,16H,1H3,(H,17,21)
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n/an/a 9.90E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222145
PNG
(2-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-...)
Show SMILES CC1(NC(=O)c2ccccc2N1)c1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClN2O/c1-15(10-6-8-11(16)9-7-10)17-13-5-3-2-4-12(13)14(19)18-15/h2-9,17H,1H3,(H,18,19)
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n/an/a 9.90E+3n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222153
PNG
(2-methyl-2-(4-methylphenyl)-6,8-dinitro-1,2,3,4-te...)
Show SMILES Cc1ccc(cc1)C1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C16H14N4O5/c1-9-3-5-10(6-4-9)16(2)17-14-12(15(21)18-16)7-11(19(22)23)8-13(14)20(24)25/h3-8,17H,1-2H3,(H,18,21)
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n/an/a 1.03E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222147
PNG
(2,2-bis(2-methylpropyl)-2,3-dihydroquinazolin-4(1H...)
Show SMILES CC(C)CC1(CC(C)C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C16H24N2O/c1-11(2)9-16(10-12(3)4)17-14-8-6-5-7-13(14)15(19)18-16/h5-8,11-12,17H,9-10H2,1-4H3,(H,18,19)
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n/an/a 1.04E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222162
PNG
(6,8-dibromo-2-methyl-2-(2-methylpropyl)-2,3-dihydr...)
Show SMILES CC(C)CC1(C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C13H16Br2N2O/c1-7(2)6-13(3)16-11-9(12(18)17-13)4-8(14)5-10(11)15/h4-5,7,16H,6H2,1-3H3,(H,17,18)
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n/an/a 1.12E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222145
PNG
(2-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-...)
Show SMILES CC1(NC(=O)c2ccccc2N1)c1ccc(Cl)cc1
Show InChI InChI=1S/C15H13ClN2O/c1-15(10-6-8-11(16)9-7-10)17-13-5-3-2-4-12(13)14(19)18-15/h2-9,17H,1H3,(H,18,19)
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n/an/a 1.12E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222152
PNG
(6,8-dinitro-2-methyl-2-propyl-2,3-dihydroquinazoli...)
Show SMILES CCCC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C12H14N4O5/c1-3-4-12(2)13-10-8(11(17)14-12)5-7(15(18)19)6-9(10)16(20)21/h5-6,13H,3-4H2,1-2H3,(H,14,17)
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n/an/a 1.21E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222154
PNG
(6,8-dinitro-2-methyl-2-(2-methylpropyl)-2,3-dihydr...)
Show SMILES CC(C)CC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N4O5/c1-7(2)6-13(3)14-11-9(12(18)15-13)4-8(16(19)20)5-10(11)17(21)22/h4-5,7,14H,6H2,1-3H3,(H,15,18)
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n/an/a 1.22E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222152
PNG
(6,8-dinitro-2-methyl-2-propyl-2,3-dihydroquinazoli...)
Show SMILES CCCC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C12H14N4O5/c1-3-4-12(2)13-10-8(11(17)14-12)5-7(15(18)19)6-9(10)16(20)21/h5-6,13H,3-4H2,1-2H3,(H,14,17)
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n/an/a 1.33E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222150
PNG
(6,8-dinitro-2-ethyl, 2-methyl-2,3-dihydroquinazoli...)
Show SMILES CCC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C11H12N4O5/c1-3-11(2)12-9-7(10(16)13-11)4-6(14(17)18)5-8(9)15(19)20/h4-5,12H,3H2,1-2H3,(H,13,16)
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n/an/a 1.39E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222151
PNG
(6,8-dinitro-2,2-diethyl-2,3-dihydroquinazolin-4(1H...)
Show SMILES CCC1(CC)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C12H14N4O5/c1-3-12(4-2)13-10-8(11(17)14-12)5-7(15(18)19)6-9(10)16(20)21/h5-6,13H,3-4H2,1-2H3,(H,14,17)
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n/an/a 1.42E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222163
PNG
(6,8-dibromo-2,2-bis(2-methylpropyl)-2,3-dihydroqui...)
Show SMILES CC(C)CC1(CC(C)C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C16H22Br2N2O/c1-9(2)7-16(8-10(3)4)19-14-12(15(21)20-16)5-11(17)6-13(14)18/h5-6,9-10,19H,7-8H2,1-4H3,(H,20,21)
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University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM10404
PNG
((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Show SMILES COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24
Show InChI InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1
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n/an/a 1.50E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222159
PNG
(6,8-dibromo-2,2-diethyl-2,3-dihydroquinazolin-4(1H...)
Show SMILES CCC1(CC)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C12H14Br2N2O/c1-3-12(4-2)15-10-8(11(17)16-12)5-7(13)6-9(10)14/h5-6,15H,3-4H2,1-2H3,(H,16,17)
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Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222146
PNG
(2-methyl-2-(2-methylpropyl)-2,3-dihydroquinazolin-...)
Show SMILES CC(C)CC1(C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C13H18N2O/c1-9(2)8-13(3)14-11-7-5-4-6-10(11)12(16)15-13/h4-7,9,14H,8H2,1-3H3,(H,15,16)
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n/an/a 1.79E+4n/an/an/an/an/an/a



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Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222159
PNG
(6,8-dibromo-2,2-diethyl-2,3-dihydroquinazolin-4(1H...)
Show SMILES CCC1(CC)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C12H14Br2N2O/c1-3-12(4-2)15-10-8(11(17)16-12)5-7(13)6-9(10)14/h5-6,15H,3-4H2,1-2H3,(H,16,17)
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Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222162
PNG
(6,8-dibromo-2-methyl-2-(2-methylpropyl)-2,3-dihydr...)
Show SMILES CC(C)CC1(C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C13H16Br2N2O/c1-7(2)6-13(3)16-11-9(12(18)17-13)4-8(14)5-10(11)15/h4-5,7,16H,6H2,1-3H3,(H,17,18)
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n/an/a 1.84E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222151
PNG
(6,8-dinitro-2,2-diethyl-2,3-dihydroquinazolin-4(1H...)
Show SMILES CCC1(CC)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C12H14N4O5/c1-3-12(4-2)13-10-8(11(17)14-12)5-7(15(18)19)6-9(10)16(20)21/h5-6,13H,3-4H2,1-2H3,(H,14,17)
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n/an/a 1.93E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222141
PNG
(2-methyl-2-phenyl-2,3-dihydroquinazolin-4(1H)-one ...)
Show SMILES CC1(NC(=O)c2ccccc2N1)c1ccccc1
Show InChI InChI=1S/C15H14N2O/c1-15(11-7-3-2-4-8-11)16-13-10-6-5-9-12(13)14(18)17-15/h2-10,16H,1H3,(H,17,18)
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Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222150
PNG
(6,8-dinitro-2-ethyl, 2-methyl-2,3-dihydroquinazoli...)
Show SMILES CCC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C11H12N4O5/c1-3-11(2)12-9-7(10(16)13-11)4-6(14(17)18)5-8(9)15(19)20/h4-5,12H,3H2,1-2H3,(H,13,16)
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n/an/a 2.07E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222148
PNG
(6,8-dinitro-2,2-dimethyl-2,3-dihydroquinazolin-4(1...)
Show SMILES CC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C10H10N4O5/c1-10(2)11-8-6(9(15)12-10)3-5(13(16)17)4-7(8)14(18)19/h3-4,11H,1-2H3,(H,12,15)
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n/an/a 2.10E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222158
PNG
(6,8-dibromo-2-ethyl, 2-methyl-2,3-dihydroquinazoli...)
Show SMILES CCC1(C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C11H12Br2N2O/c1-3-11(2)14-9-7(10(16)15-11)4-6(12)5-8(9)13/h4-5,14H,3H2,1-2H3,(H,15,16)
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n/an/a 2.21E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222147
PNG
(2,2-bis(2-methylpropyl)-2,3-dihydroquinazolin-4(1H...)
Show SMILES CC(C)CC1(CC(C)C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C16H24N2O/c1-11(2)9-16(10-12(3)4)17-14-8-6-5-7-13(14)15(19)18-16/h5-8,11-12,17H,9-10H2,1-4H3,(H,18,19)
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n/an/a 2.34E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222160
PNG
(6,8-dibromo-2-methyl-2-propyl-2,3-dihydroquinazoli...)
Show SMILES CCCC1(C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C12H14Br2N2O/c1-3-4-12(2)15-10-8(11(17)16-12)5-7(13)6-9(10)14/h5-6,15H,3-4H2,1-2H3,(H,16,17)
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Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222148
PNG
(6,8-dinitro-2,2-dimethyl-2,3-dihydroquinazolin-4(1...)
Show SMILES CC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C10H10N4O5/c1-10(2)11-8-6(9(15)12-10)3-5(13(16)17)4-7(8)14(18)19/h3-4,11H,1-2H3,(H,12,15)
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n/an/a 2.44E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222141
PNG
(2-methyl-2-phenyl-2,3-dihydroquinazolin-4(1H)-one ...)
Show SMILES CC1(NC(=O)c2ccccc2N1)c1ccccc1
Show InChI InChI=1S/C15H14N2O/c1-15(11-7-3-2-4-8-11)16-13-10-6-5-9-12(13)14(18)17-15/h2-10,16H,1H3,(H,17,18)
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n/an/a 2.45E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222156
PNG
(6,8-dibromo-2,2-dimethyl-2,3-dihydroquinazolin-4(1...)
Show SMILES CC1(C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C10H10Br2N2O/c1-10(2)13-8-6(9(15)14-10)3-5(11)4-7(8)12/h3-4,13H,1-2H3,(H,14,15)
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222158
PNG
(6,8-dibromo-2-ethyl, 2-methyl-2,3-dihydroquinazoli...)
Show SMILES CCC1(C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C11H12Br2N2O/c1-3-11(2)14-9-7(10(16)15-11)4-6(12)5-8(9)13/h4-5,14H,3H2,1-2H3,(H,15,16)
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n/an/a 2.94E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222142
PNG
(2-ethyl-2-methyl-2,3-dihydroquinazolin-4(1H)-one (...)
Show SMILES CCC1(C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C11H14N2O/c1-3-11(2)12-9-7-5-4-6-8(9)10(14)13-11/h4-7,12H,3H2,1-2H3,(H,13,14)
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n/an/a 2.94E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222146
PNG
(2-methyl-2-(2-methylpropyl)-2,3-dihydroquinazolin-...)
Show SMILES CC(C)CC1(C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C13H18N2O/c1-9(2)8-13(3)14-11-7-5-4-6-10(11)12(16)15-13/h4-7,9,14H,8H2,1-3H3,(H,15,16)
UniProtKB/SwissProt

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UniChem
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n/an/a 3.10E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222144
PNG
(2-methyl-2-propyl-2,3-dihydroquinazolin-4(1H)-one ...)
Show SMILES CCCC1(C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C12H16N2O/c1-3-8-12(2)13-10-7-5-4-6-9(10)11(15)14-12/h4-7,13H,3,8H2,1-2H3,(H,14,15)
UniProtKB/SwissProt

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n/an/a 3.11E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222144
PNG
(2-methyl-2-propyl-2,3-dihydroquinazolin-4(1H)-one ...)
Show SMILES CCCC1(C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C12H16N2O/c1-3-8-12(2)13-10-7-5-4-6-9(10)11(15)14-12/h4-7,13H,3,8H2,1-2H3,(H,14,15)
PDB
MMDB

UniProtKB/TrEMBL

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n/an/a 3.34E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222143
PNG
(2,2-diethyl-2,3-dihydroquinazolin-4(1H)-one (3d))
Show SMILES CCC1(CC)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C12H16N2O/c1-3-12(4-2)13-10-8-6-5-7-9(10)11(15)14-12/h5-8,13H,3-4H2,1-2H3,(H,14,15)
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n/an/a 5.42E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222143
PNG
(2,2-diethyl-2,3-dihydroquinazolin-4(1H)-one (3d))
Show SMILES CCC1(CC)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C12H16N2O/c1-3-12(4-2)13-10-8-6-5-7-9(10)11(15)14-12/h5-8,13H,3-4H2,1-2H3,(H,14,15)
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n/an/a 5.79E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222142
PNG
(2-ethyl-2-methyl-2,3-dihydroquinazolin-4(1H)-one (...)
Show SMILES CCC1(C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C11H14N2O/c1-3-11(2)12-9-7-5-4-6-8(9)10(14)13-11/h4-7,12H,3H2,1-2H3,(H,13,14)
PDB
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n/an/a 5.83E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM222140
PNG
(2,2- dimethyl-2,3-dihydroquinazolin-4(1H)-one (3a))
Show SMILES CC1(C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C10H12N2O/c1-10(2)11-8-6-4-3-5-7(8)9(13)12-10/h3-6,11H,1-2H3,(H,12,13)
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n/an/a 8.03E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222156
PNG
(6,8-dibromo-2,2-dimethyl-2,3-dihydroquinazolin-4(1...)
Show SMILES CC1(C)NC(=O)c2cc(Br)cc(Br)c2N1
Show InChI InChI=1S/C10H10Br2N2O/c1-10(2)13-8-6(9(15)14-10)3-5(11)4-7(8)12/h3-4,13H,1-2H3,(H,14,15)
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n/an/a 8.62E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM222140
PNG
(2,2- dimethyl-2,3-dihydroquinazolin-4(1H)-one (3a))
Show SMILES CC1(C)NC(=O)c2ccccc2N1
Show InChI InChI=1S/C10H12N2O/c1-10(2)11-8-6-4-3-5-7(8)9(13)12-10/h3-6,11H,1-2H3,(H,12,13)
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n/an/a 9.75E+4n/an/an/an/an/an/a



University of Sargodha



Assay Description
Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...


Bioorg Chem 70: 237-244 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.004
BindingDB Entry DOI: 10.7270/Q2M0448Z
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%