Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with all data for entry = 50049258
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50029207((E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethy...)
Affinity DataIC50:  130nMAssay Description:Inhibition of thapsigargin-stimulated 15-LOX in human primary polymorphonuclear leukocytes using arachidonic acid as substrate preincubated for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  400nMAssay Description:Binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma) was determined by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50237598(CHEMBL395428 | US11660306, Example Boswellic acid)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of 15-LOX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed