BindingDB logo
myBDB logout

PubMed code 2859372

Compile data set for download or QSAR
Found 7 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(Mus musculus)
BDBM50225515
PNG
(CHEMBL345618)
Show SMILES CC(CCCCNC(=O)OCc1ccccc1)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H30N2O5/c1-16(24-14-21(27)18-10-11-19(25)20(26)13-18)7-5-6-12-23-22(28)29-15-17-8-3-2-4-9-17/h2-4,8-11,13,16,21,24-27H,5-7,12,14-15H2,1H3,(H,23,28)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 49n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Effective concentration against 125I]iodocyanopindolol(ICYP) binding to beta adrenergic receptor was determined


J Med Chem 28: 634-42 (1985)


Article DOI: 10.1021/jm50001a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Mus musculus)
BDBM50225512
PNG
(CHEMBL157187)
Show SMILES CC(CCCCNC(=O)c1ccc(C)cc1)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H30N2O4/c1-15-6-8-17(9-7-15)22(28)23-12-4-3-5-16(2)24-14-21(27)18-10-11-19(25)20(26)13-18/h6-11,13,16,21,24-27H,3-5,12,14H2,1-2H3,(H,23,28)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
KD constant value was evaluated for the displacement of ICYP (iodocyanopindolol) binding


J Med Chem 28: 634-42 (1985)


Article DOI: 10.1021/jm50001a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Mus musculus)
BDBM50225514
PNG
(CHEMBL160277)
Show SMILES CC(CCCCN)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H24N2O3/c1-10(4-2-3-7-15)16-9-14(19)11-5-6-12(17)13(18)8-11/h5-6,8,10,14,16-19H,2-4,7,9,15H2,1H3
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0.0000100n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
KD constant value was evaluated for the displacement of ICYP (iodocyanopindolol) binding


J Med Chem 28: 634-42 (1985)


Article DOI: 10.1021/jm50001a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Mus musculus)
BDBM50225516
PNG
(CHEMBL156326)
Show SMILES NCCCNCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H18N2O3/c12-4-1-5-13-7-11(16)8-2-3-9(14)10(15)6-8/h2-3,6,11,13-16H,1,4-5,7,12H2
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.60E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Effective concentration against 125I]iodocyanopindolol(ICYP) binding to beta adrenergic receptor was determined


J Med Chem 28: 634-42 (1985)


Article DOI: 10.1021/jm50001a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Mus musculus)
BDBM50225513
PNG
(CHEMBL423055)
Show SMILES CC(CCCCNC(=O)Nc1ccc(C)cc1)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H31N3O4/c1-15-6-9-18(10-7-15)25-22(29)23-12-4-3-5-16(2)24-14-21(28)17-8-11-19(26)20(27)13-17/h6-11,13,16,21,24,26-28H,3-5,12,14H2,1-2H3,(H2,23,25,29)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
KD constant value was evaluated for the displacement of ICYP (iodocyanopindolol) binding in SF-49 lymphoma cell


J Med Chem 28: 634-42 (1985)


Article DOI: 10.1021/jm50001a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Mus musculus)
BDBM25392
PNG
(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Show SMILES CC(C)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 980n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Effective concentration against 125I]iodocyanopindolol(ICYP) binding to beta adrenergic receptor was determined


J Med Chem 28: 634-42 (1985)


Article DOI: 10.1021/jm50001a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Mus musculus)
BDBM50225511
PNG
(CHEMBL160788)
Show SMILES CC(CCCCCNC(=O)OCc1ccccc1)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C23H32N2O5/c1-17(25-15-22(28)19-11-12-20(26)21(27)14-19)8-4-3-7-13-24-23(29)30-16-18-9-5-2-6-10-18/h2,5-6,9-12,14,17,22,25-28H,3-4,7-8,13,15-16H2,1H3,(H,24,29)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 8.70n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Effective concentration against 125I]iodocyanopindolol(ICYP) binding to beta adrenergic receptor was determined


J Med Chem 28: 634-42 (1985)


Article DOI: 10.1021/jm50001a017
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%