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Found 13 Enz. Inhib. hit(s) with all data for entry = 50001038
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268191(CHEMBL4102765)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268184(CHEMBL4060026)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268190(CHEMBL4099888)
Affinity DataIC50:  3.52E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268187(CHEMBL4104323)
Affinity DataIC50:  5.57E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268185(CHEMBL4088260)
Affinity DataIC50:  6.45E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268189(CHEMBL4081883)
Affinity DataIC50:  8.92E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268172(CHEMBL4061636)
Affinity DataIC50:  9.91E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268188(CHEMBL4089751)
Affinity DataIC50:  1.37E+5nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268186(CHEMBL4089711)
Affinity DataIC50:  1.76E+5nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268173(CHEMBL4069708)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268192(CHEMBL4086302)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed