Affinity DataIC50: 1.30nMAssay Description:Inhibition of TBK1 (unknown origin)More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of IKKepsilon (unknown origin)More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 5.90nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 725nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 104nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 1.04E+3nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 4.60nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataKd: 70nMAssay Description:Binding affinity to human full length wild-type IKKepsilon expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 245nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 270nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 275nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair