Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50002548
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459898(CHEMBL4227907)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of TBK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459898(CHEMBL4227907)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of IKKepsilon (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50459896(CHEMBL4226250)
Affinity DataIC50:  800nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50099062(CHEMBL3344081 | US10730870, Example 3 | US11512083...)
Affinity DataIC50:  800nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
LigandPNGBDBM50459898(CHEMBL4227907)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50459907(CHEMBL4225691)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50459913(CHEMBL4227623)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50459906(CHEMBL4226773)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50459899(CHEMBL4226398)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50459905(CHEMBL4227365)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50459909(CHEMBL4226693)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459908(CHEMBL4224757)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459909(CHEMBL4226693)
Affinity DataKd:  5.90nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459900(CHEMBL4228346)
Affinity DataKd:  725nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459910(CHEMBL4228790)
Affinity DataKd:  104nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459911(CHEMBL4225766)
Affinity DataKd:  4nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459912(CHEMBL4225995)
Affinity DataKd:  1.04E+3nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459898(CHEMBL4227907)
Affinity DataKd:  4.60nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459898(CHEMBL4227907)
Affinity DataKd:  70nMAssay Description:Binding affinity to human full length wild-type IKKepsilon expressed in mammalian expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459897(CHEMBL4226319)
Affinity DataKd:  10nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459901(CHEMBL4226591)
Affinity DataKd:  13nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459896(CHEMBL4226250)
Affinity DataKd:  245nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459902(CHEMBL4227342)
Affinity DataKd:  270nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459903(CHEMBL4226837)
Affinity DataKd:  275nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas

Curated by ChEMBL
LigandPNGBDBM50459904(CHEMBL4227097)
Affinity DataKd:  130nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed