Found 37 Enz. Inhib. hit(s) with all data for entry = 50001159 
Affinity DataIC50: 75nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of human full-length His-tagged USP8 expressed baculovirus infected insect cells using Ub-AMC as substrate by fluorescence spectroscopic a...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant 6His-tagged USP7 using Ub-Rh110 as substrate preincubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rh110 as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: <200nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rh110 as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rh110 as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rh110 as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of full length wild-type human N-terminal His-tagged USP7 expressed in baculovirus infected Sf9 cells using Ub-AMC as substrate preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant 6His-tagged USP7 using Ub-Rh110 as substrate preincubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rh110 as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of human recombinant 6His-tagged USP7 using Ub-Rh110 as substrate preincubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of full-length native C-terminal USP7 (unknown origin) using Ub-Rho110 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human full-length wild-type N-terminal His-tagged USP7 expressed in baculovirus infected Sf9 cells using Ub-AMC as substrate preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 20 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of full-length recombinant USP7 (unknown origin) expressed in Sf9 cells using Ub-EKL as substrate preincubated for 30 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of full-length native C-terminal USP7 (unknown origin) using Ub-Rho110 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of full-length USP7 (unknown origin) using Ub-AMC as substrate preincubated for 20 mins followed by substrate addition measured after 50 m...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of full-length recombinant USP7 (unknown origin) expressed in Sf9 cells using Ub-EKL as substrate preincubated for 30 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of USP7 (unknown origin) using human N-terminal GST-tagged UBA52 as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of USP7 (unknown origin) using GST-Ub52-flag substrate incubated for 1 hr by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of USP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of USP7 (unknown origin) using human N-terminal GST-tagged UBA52 as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of USP47 (unknown origin) using Ub-AMC as substrate preincubated for 20 mins followed by substrate addition measured after 50 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human full-length wild-type His-tagged catalytic USP7 C223A mutant expressed in baculovirus infected Sf9 cells using Ub-AMC as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of full-length recombinant USP7 (unknown origin) expressed in Sf9 cells using Ub-EKL as substrate preincubated for 30 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: >6.33E+4nMAssay Description:Inhibition of full-length native C-terminal USP7 (unknown origin) using Ub-Rho110 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of USP8 (unknown origin) expressed in baculovirus infected Sf9 cells using Ub-AMC as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Progenra
Curated by ChEMBL
Progenra
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of UCH-L3 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Progenra
Curated by ChEMBL
Progenra
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of UCH-L1 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of USP5 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Caspase 3 (unknown origin) using Ac-DEVD-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 min...More data for this Ligand-Target Pair
