Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50000814
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50398668(CHEMBL2178134 | US8802674, 256)
Affinity DataIC50:  97nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50398668(CHEMBL2178134 | US8802674, 256)
Affinity DataIC50:  97nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223552(US9321748, 12)
Affinity DataIC50:  160nMAssay Description:Inhibition of human BRD4 bromo domain 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223552(US9321748, 12)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223553(US9321748, 13)
Affinity DataIC50:  340nMAssay Description:Inhibition of human BRD4 bromo domain 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223553(US9321748, 13)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223554(US9321748, 14)
Affinity DataIC50:  340nMAssay Description:Inhibition of C-terminal biotin-labelled BCoR/wild-type BCL6 BTB domain (unknown origin) protein-protein interaction by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223546(US9321748, 6)
Affinity DataIC50:  490nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223546(US9321748, 6)
Affinity DataIC50:  490nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223549(US9321748, 9)
Affinity DataIC50:  540nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membranes after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223549(US9321748, 9)
Affinity DataIC50:  550nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223554(US9321748, 14)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223541(US9321748, 1)
Affinity DataIC50:  910nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223552(US9321748, 12)
Affinity DataIC50:  920nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223543(US9321748, 3)
Affinity DataIC50:  970nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223543(US9321748, 3)
Affinity DataIC50:  970nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223542(US9321748, 2)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223542(US9321748, 2)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223552(US9321748, 12)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human BRD4 bromo domain 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50260922(CHEMBL4060747)
Affinity DataIC50:  2.20E+3nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50260922(CHEMBL4060747)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50470161(CHEMBL4091112)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50470158(CHEMBL4103716)
Affinity DataIC50:  3.60E+3nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50470157(CHEMBL4098856)
Affinity DataIC50:  5.80E+3nMAssay Description:Displacement of A488-SMRT from BCL6 BTB domain (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50260924(CHEMBL4104344)
Affinity DataIC50:  6.70E+3nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50470160(CHEMBL4069384)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50260923(CHEMBL4092594)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50260923(CHEMBL4092594)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of C-terminal biotin-labelled BCoR/wild-type BCL6 BTB domain (unknown origin) protein-protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50470159(CHEMBL4096615)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of C-terminal biotin-labelled BCoR/wild-type BCL6 BTB domain (unknown origin) protein-protein interaction by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50470156(CHEMBL4100328)
Affinity DataIC50:  1.30E+4nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50260924(CHEMBL4104344)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50260925(CHEMBL4095694)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50260925(CHEMBL4095694)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of C-terminal biotin-labelled BCoR/wild-type BCL6 BTB domain (unknown origin) protein-protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50470162(CHEMBL4064894)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of human BRD4 bromodomain2 by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed