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PubMed code 28841282

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAD51-BRCA2 BRC repeat complex


(Homo sapiens (Human))
BDBM65520
PNG
(N-cyclopentyl-2-((5-((2-oxobenzo[d]thiazol-3(2H)-y...)
Show SMILES O=C(CSc1nnc(Cn2c3ccccc3sc2=O)n1CCCc1ccccc1)NC1CCCC1
Show InChI InChI=1S/C26H29N5O2S2/c32-24(27-20-12-4-5-13-20)18-34-25-29-28-23(30(25)16-8-11-19-9-2-1-3-10-19)17-31-21-14-6-7-15-22(21)35-26(31)33/h1-3,6-7,9-10,14-15,20H,4-5,8,11-13,16-18H2,(H,27,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.50E+4n/an/an/an/a



Istituto Italiano di Tecnologia



Assay Description
This assay is an efficient tool for directly measuring inhibition of the BRC4−Rad51 interaction, at a molecular level, which is described by Ra...


ACS Chem Biol 12: 2491-2497 (2017)


Article DOI: 10.1021/acschembio.7b00707
BindingDB Entry DOI: 10.7270/Q2WS8RD4
More data for this
Ligand-Target Pair
RAD51-BRCA2 BRC repeat complex


(Homo sapiens (Human))
BDBM65519
PNG
(F0665-0303 | N-cyclopentyl-2-((5-((2-oxobenzo[d]th...)
Show SMILES O=C(CSc1nnc(Cn2c3ccccc3sc2=O)n1CCc1ccccc1)NC1CCCC1
Show InChI InChI=1S/C25H27N5O2S2/c31-23(26-19-10-4-5-11-19)17-33-24-28-27-22(29(24)15-14-18-8-2-1-3-9-18)16-30-20-12-6-7-13-21(20)34-25(30)32/h1-3,6-9,12-13,19H,4-5,10-11,14-17H2,(H,26,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.30E+4n/an/an/an/a



Istituto Italiano di Tecnologia



Assay Description
This assay is an efficient tool for directly measuring inhibition of the BRC4−Rad51 interaction, at a molecular level, which is described by Ra...


ACS Chem Biol 12: 2491-2497 (2017)


Article DOI: 10.1021/acschembio.7b00707
BindingDB Entry DOI: 10.7270/Q2WS8RD4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%