Compile Data Set for Download or QSAR
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Found 30 Enz. Inhib. hit(s) with all data for entry = 50001383
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277499(CHEMBL4170726)
Affinity DataIC50:  6.30E+3nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277475(CHEMBL4171556)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277517(CHEMBL4161953)
Affinity DataIC50:  8.30E+3nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277512(CHEMBL4176401)
Affinity DataIC50:  1.18E+4nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277497(CHEMBL2359609)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277474(CHEMBL4160118)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277493(CHEMBL4165794)
Affinity DataIC50:  3.57E+4nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277472(CHEMBL4161295)
Affinity DataIC50:  3.61E+4nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277524(CHEMBL4169225)
Affinity DataIC50:  3.90E+4nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277513(CHEMBL4173018)
Affinity DataIC50:  4.18E+4nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277516(CHEMBL4172609)
Affinity DataIC50:  4.41E+4nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277520(CHEMBL4164608)
Affinity DataIC50:  5.82E+4nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277546(CHEMBL4169621)
Affinity DataIC50:  6.79E+4nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277521(CHEMBL4175237)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277522(CHEMBL4168041)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277523(CHEMBL4164711)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277519(CHEMBL4168816)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277518(CHEMBL4160880)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277515(CHEMBL4173713)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277514(CHEMBL4177482)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277502(CHEMBL4165793)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277501(CHEMBL4169224)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277500(CHEMBL4172644)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277498(CHEMBL4176066)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277496(CHEMBL4162344)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277495(CHEMBL4177082)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277484(CHEMBL2141695)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277483(CHEMBL4172607)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277547(CHEMBL4162293)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50277473(CHEMBL4170264)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed