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Found 80 Enz. Inhib. hit(s) with all data for entry = 50000142
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50435378(CHEMBL1586371)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241448(CHEMBL4064385)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241450(CHEMBL4072816)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant HDAC6 expressed in Baculovirus infected Sf9 cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241438(CHEMBL4065412)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate after 3 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241438(CHEMBL4065412)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241480(CHEMBL4089517)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241448(CHEMBL4064385)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241479(CHEMBL4081313)
Affinity DataIC50:  46nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human recombinant HDAC3/GST tagged NCOR1 (397 to 503 residues) expressed in insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate prei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241438(CHEMBL4065412)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19422(4-(acetylamino)-N-(2-amino-phenyl) benzamide | CI-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate after 3 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241474(CHEMBL4081642)
Affinity DataIC50:  71nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241438(CHEMBL4065412)
Affinity DataIC50:  75nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241481(CHEMBL4080695)
Affinity DataIC50:  83nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241475(CHEMBL4061360)
Affinity DataIC50:  84nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241473(CHEMBL4099640)
Affinity DataIC50:  87nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241440(CHEMBL4070033)
Affinity DataIC50:  93nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241483(CHEMBL4101228)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241442(CHEMBL4092869)
Affinity DataIC50:  116nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  149nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition mea...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241478(CHEMBL4092530)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241462(CHEMBL4084779)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241443(CHEMBL4092104)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241443(CHEMBL4092104)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241477(CHEMBL4098798)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241463(CHEMBL4074493)
Affinity DataIC50:  220nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241465(CHEMBL4093482)
Affinity DataIC50:  220nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241469(CHEMBL4065864)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241441(CHEMBL4097225)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241449(CHEMBL4061419)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241456(CHEMBL4069085)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241451(CHEMBL4099703)
Affinity DataIC50:  280nMAssay Description:Effect of Phosphatidylserine on inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241458(CHEMBL4071747)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241459(CHEMBL4063132)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241452(CHEMBL4080754)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241457(CHEMBL4096345)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241476(CHEMBL4083264)
Affinity DataIC50:  370nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241482(CHEMBL4070085)
Affinity DataIC50:  440nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241465(CHEMBL4093482)
Affinity DataIC50:  550nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241469(CHEMBL4065864)
Affinity DataIC50:  620nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241471(CHEMBL4105561)
Affinity DataIC50:  670nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM19422(4-(acetylamino)-N-(2-amino-phenyl) benzamide | CI-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241442(CHEMBL4092869)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241438(CHEMBL4065412)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of human recombinant HDAC3/GST tagged NCOR1 (397 to 503 residues) expressed in insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate prei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241456(CHEMBL4069085)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241455(CHEMBL4091055)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50241458(CHEMBL4071747)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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