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Found 43 Enz. Inhib. hit(s) with all data for entry = 50002329
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50:  50nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50:  160nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50:  190nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50:  210nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33857(MLS000708242 | SMR000287709 | [5-amino-3-(2-furany...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50:  400nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33857(MLS000708242 | SMR000287709 | [5-amino-3-(2-furany...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50:  490nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50:  600nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457205(CHEMBL4217303)
Affinity DataIC50:  600nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50:  750nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50:  810nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33857(MLS000708242 | SMR000287709 | [5-amino-3-(2-furany...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33857(MLS000708242 | SMR000287709 | [5-amino-3-(2-furany...)
Affinity DataIC50:  860nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50:  970nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457219(CHEMBL4212345)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33601((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(2-met...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50:  4.97E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50:  5.27E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM33882((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-chl...)
Affinity DataIC50:  5.83E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50326570((1H-benzo[d][1,2,3]triazol-1-yl)(2-methoxyphenyl)m...)
Affinity DataIC50:  7.21E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457204(CHEMBL4212867)
Affinity DataIC50:  8.37E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457201(CHEMBL1288788)
Affinity DataIC50:  9.39E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457215(CHEMBL4203609)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457214(CHEMBL1290554)
Affinity DataIC50:  2.54E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM32806(1-benzotriazolyl-(3,4-dimethoxyphenyl)methanone | ...)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457218(CHEMBL4212996)
Affinity DataIC50:  3.17E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457213(CHEMBL4217931)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457211(CHEMBL4205076)
Affinity DataIC50:  4.36E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457216(CHEMBL4211728)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457207(CHEMBL4215216)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457210(CHEMBL1163357)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457209(CHEMBL4202629)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457208(CHEMBL4206846)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50360399(CHEMBL1933870)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457217(CHEMBL4210280)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
The University Of Akron

Curated by ChEMBL
LigandPNGBDBM50457212(CHEMBL4207366)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed