BindingDB PrimarySearch

Found 3 Enz. Inhib. hit(s) with all data for entry = 50002023

Tyrosine-protein kinase SYK(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)

Ki: 5.00E+3nMAssay Description:Binding affinity to recombinant full length human N-terminal GST-tagged Syk-KD (356 to 635 residues) cytoplasmic domain expressed in baculovirus infe...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Integrin alpha-IIb/beta-3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50124573(CHEMBL1472460)

IC50: 96nMAssay Description:Antagonist activity at integrin alpha2b beta3 receptor in citrated human platelet-rich plasma assessed as inhibition of ADP-induced platelets aggrega...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Integrin alpha-IIb/beta-3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50124572(CHEMBL1234739)

IC50: 9.60E+3nMAssay Description:Antagonist activity at integrin alpha2b beta3 receptor in citrated human platelet-rich plasma assessed as inhibition of ADP-induced platelets aggrega...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)