Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 50000366
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50247638(CHEMBL4101883)
Affinity DataKi: <1nMAssay Description:Inhibition of FITC-Bim binding to human His6-MPB tagged MCL1 expressed in Escherichia coli K-12 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyketide synthase Pks13(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50247640(CHEMBL4063356)
Affinity DataIC50:  260nMAssay Description:Inhibition of Mycobacterium tuberculosis ATCC 25618 H37Rv Pks13 thioesterase domain expressed in Escherichia coli BL21(DE3) using 4-MUH as substrate ...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50247639(CHEMBL4068716)
Affinity DataIC50:  498nMAssay Description:Inhibition of Pseudomonas aeruginosa metallobeta-lactamase-2 expressed in Escherichia coli by fluorogenic assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Tetrahymena thermophila)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50247636(CHEMBL4099615)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of N-terminal His-tagged Tetrahymena thermophila PARG expressed in Escherichia coli Rosetta2(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target14-3-3 protein zeta/delta(Homo sapiens)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of PRAS40 binding to human GST-tagged 14-3-3 protein zeta/delta expressed in Escherichia coli BL21(DE3) by ELISAMore data for this Ligand-Target Pair
TargetCys-loop ligand-gated ion channel(Dickeya chrysanthemi)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataIC50:  1.58E+5nMAssay Description:Inhibition of Erwinia chrysanthemi N-terminal MBP-fused pentameric ligand gated ion channel expressed in Escherichia coli C43 by electrophysiology me...More data for this Ligand-Target Pair
TargetB-cell lymphoma 6 protein(Homo sapiens)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50247637(CHEMBL4069658)
Affinity DataIC50:  2.12E+5nMAssay Description:Displacement of A633-labeled SMRT-BBD peptide from human BCL6 BTB domain expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMajor prion protein(Mus musculus)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataEC50:  2.00E+3nMAssay Description:Activity at mouse prion protein expressed in Escherichia coliMore data for this Ligand-Target Pair