TargetHistone acetyltransferase(Tetrahymena thermophila (strain SB210))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of Tetrahymena Gcn5 (48 to 210 residues) using histone (3 to 20 residues) peptide substrate in presence of [14C]acetyl CoA by phosphor ima...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human His-tagged MOF using histone H4 substrate by radioactive acetylation assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human His-tagged MOF using histone H4 substrate by radioactive acetylation assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human His-tagged MOF using histone H4 substrate by radioactive acetylation assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of p300/CBP (unknown origin)More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human His-tagged MOF using histone H4 substrate by radioactive acetylation assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human His-tagged MOF using histone H4 substrate by radioactive acetylation assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human His-tagged MOF using histone H4 substrate by radioactive acetylation assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2A(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Gcn5 using H3 as substrate in presence of [3H]-acetyl-CoA by phosphor image analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 1.90E+4nMAssay Description:Binding affinity to human His-tagged MOF by SPR analysisMore data for this Ligand-Target Pair