Found 18 Enz. Inhib. hit(s) with all data for entry = 50003301 TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human GST-tagged BRAF V600E mutant (AA416 to 766 residues (unknown origin) using full length His6-tagged MEK1 as substrate ...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of CRAF (unknown origin)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CRAF (unknown origin) after 20 mins in presence of 33P-gamma-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of BRAF (unknown origin) using full length His6-tagged MEK1 as substrate after 20 mins in presence of 33P-gamma-ATP by hotspot kinase assa...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase A-Raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of ARAF (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase A-Raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of ARAF (unknown origin) after 20 mins in presence of 33P-gamma-ATP by hotspot kinaseMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of CRAF (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)
Curated by ChEMBL
University Of Science & Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)