Compile Data Set for Download or QSAR
maximum 50k data
Found 67 Enz. Inhib. hit(s) with all data for entry = 50007813
LigandPNGBDBM50512885(CHEMBL4441003)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512862(CHEMBL4541570)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512880(CHEMBL4468379)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of PI3Kdelta in human SUDHL6 cellsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM236918(US9388189, 1)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512872(CHEMBL4470131)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM350391((S)-4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512875(CHEMBL4567071)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512883(CHEMBL4460140)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512863(CHEMBL4466137)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512884(CHEMBL4557936)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512861(CHEMBL4558527)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50234169(CHEMBL4101902)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512877(CHEMBL4451200)
Affinity DataIC50: <1nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512878(CHEMBL4438682)
Affinity DataIC50: <1nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM272573(US10065963, 32c | US10376513, Example 346 | US1064...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PI3Kdelta in human B-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512881(CHEMBL4435921)
Affinity DataIC50: <1nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512869(CHEMBL4463183)
Affinity DataIC50:  1nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM333922(8-(1-ethyl-5-methyl-1H-pyrazol- 4-yl)-9-methyl-6-{...)
Affinity DataIC50: <1nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512882(CHEMBL4516283)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM172643(US9090628, 303)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512864(CHEMBL4530831)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM188116(US9670194, Ex. 1 (S)-2-(1-((6-amino-5-(5-methyl-1,...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50193031(CHEMBL3959351 | US11155556, No. 12)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50:  2.5nMAssay Description:Inhibition of GST-tagged PI3Kdelta in human U937 cells using PIP2 as substrate preincubated for 10 mins followed by ATP addition measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PI3Kdelta in basophil derived from B-cell malignant patientMore data for this Ligand-Target Pair
LigandPNGBDBM50193013(Duvelisib | INK-1147 | INK-1197 | IPI-145)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PI3Kdelta in human Raji cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512886(CHEMBL4441821)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512865(CHEMBL4441870)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant N-terminal His-tagged full length human PI3Kgamma expressed in baculovirus expression system after 80 mins by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM204084(US9539260, F1)
Affinity DataIC50:  3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using phosphatidyl inositol as substrate in presence of [33P]ATP by by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512865(CHEMBL4441870)
Affinity DataIC50:  4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512882(CHEMBL4516283)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512876(CHEMBL4436260)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM36411(2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512867(CHEMBL4444179)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512868(CHEMBL4543628)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512867(CHEMBL4444179)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512871(CHEMBL4457478)
Affinity DataIC50:  11nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512879(Seletalisib | UCB-5857 | Ucb5857)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3Kdelta in human Neutrophil cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM200639(US9227977, Compound A)
Affinity DataIC50:  12nMAssay Description:Inhibition of GST-tagged PI3Kdelta in human U937 cells using PIP2 as substrate preincubated for 10 mins followed by ATP addition measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM184556(US9150579, B1)
Affinity DataIC50:  14nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 10 mins followed by ATP addition measured after 30 mins by HTRF ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512873(CHEMBL4584110)
Affinity DataIC50: <20nMAssay Description:Inhibition of PI3Kdelta in human SU-DHL6 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512874(CHEMBL4527417)
Affinity DataIC50: <20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512870(Tenalisib)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM200639(US9227977, Compound A)
Affinity DataIC50:  25nMAssay Description:Inhibition of GST-tagged PI3Kgamma in human U937 cells using PIP2 as substrate preincubated for 10 mins followed by ATP addition measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50193013(Duvelisib | INK-1147 | INK-1197 | IPI-145)
Affinity DataIC50:  27nMAssay Description:Inhibition of PI3Kgamma in human Raji cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50:  28nMAssay Description:Inhibition of GST-tagged PI3Kgamma in human U937 cells using PIP2 as substrate preincubated for 10 mins followed by ATP addition measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50004547(CHEMBL2216863 | US10065963, Compound 28 | US104280...)
Affinity DataIC50:  31nMAssay Description:Inhibition of PI3Kdelta in basophil derived from B-cell malignant patientMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512870(Tenalisib)
Affinity DataIC50:  33nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512880(CHEMBL4468379)
Affinity DataIC50:  34nMAssay Description:Inhibition of PI3Kgamma in human SUDHL6 cellsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM350391((S)-4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]...)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant N-terminal His-tagged full length human PI3Kgamma expressed in baculovirus expression system after 80 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 67 total ) | Next | Last >>
Jump to: