Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50002426
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50: >10nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022224(2-Imidazol-1-ylmethyl-benzofuran-5-carboxylic acid...)
Affinity DataIC50:  12nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50:  17nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022219(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-6...)
Affinity DataIC50:  18nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022220(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-5...)
Affinity DataIC50:  22nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022226(6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...)
Affinity DataIC50:  25nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022230(3-Bromo-2-imidazol-1-ylmethyl-benzo[b]thiophene-5-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022215(3-Bromo-2-imidazol-1-ylmethyl-benzofuran-5-carboxy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022223(3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...)
Affinity DataIC50:  31nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022221(2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-car...)
Affinity DataIC50:  32nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50:  34nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022229(6-Imidazol-1-ylmethyl-naphthalene-2-carboxylic aci...)
Affinity DataIC50:  34nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022218(2-Imidazol-1-ylmethyl-3-methyl-1H-indole-5-carboxy...)
Affinity DataIC50:  37nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022227(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-6...)
Affinity DataIC50:  40nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022228(2-Imidazol-1-ylmethyl-3-methylsulfanyl-benzo[b]thi...)
Affinity DataIC50:  43nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022225(6-Imidazol-1-ylmethyl-naphthalene-1-carboxylic aci...)
Affinity DataIC50:  71nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022230(3-Bromo-2-imidazol-1-ylmethyl-benzo[b]thiophene-5-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022223(3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022226(6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022223(3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022219(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-6...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022227(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-6...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022226(6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022221(2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-car...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022219(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-6...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022220(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-5...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022227(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-6...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50022223(3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed