Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50008984
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50274121(CHEMBL4127092)
Affinity DataIC50:  27nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50274124(CHEMBL4125966 | US10793591, Compound 12)
Affinity DataIC50:  39nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50524197(CHEMBL4555315 | US10793591, Compound 46)
Affinity DataIC50:  110nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50274118(CHEMBL4127030 | US10793591, Compound 7a)
Affinity DataIC50:  140nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50524193(CHEMBL4543543)
Affinity DataIC50:  150nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50524191(CHEMBL4592496)
Affinity DataIC50:  190nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50524198(CHEMBL4592592)
Affinity DataIC50:  280nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50239939(CHEMBL4088430)
Affinity DataIC50:  300nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50274117(CHEMBL4127921)
Affinity DataIC50:  330nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50524194(CHEMBL4454742)
Affinity DataIC50:  340nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50524192(CHEMBL4440367 | US10793591, Compound 26)
Affinity DataIC50:  860nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50524195(CHEMBL4522072)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50524196(CHEMBL4546003)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template me...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed