BindingDB PrimarySearch

Found 102 Enz. Inhib. hit(s) with all data for entry = 50004507

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

IC50: 19nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502268(CHEMBL4447813)

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502278(CHEMBL4438193)

IC50: 22nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502278(CHEMBL4438193)

IC50: 26nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) demyristoylase activity expressed in Escherichia coli using p5...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502270(CHEMBL4458848)

IC50: 31nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity expressed in Escherichia coli Rosetta2 using Fluor-de-Lys-SIRT2 deacetylase substrate meas...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502267(CHEMBL4457496)

IC50: 36nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502269(CHEMBL4446458)

IC50: 44nMAssay Description:Inhibition of recombinant human SIRT2 demyristoylase activity using p53(Myr)-AMC as substrate measured after 3 hrs in presence of NAD+ and trypsin by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502278(CHEMBL4438193)

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502278(CHEMBL4438193)

IC50: 46nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) defatty-acylase activity expressed in Escherichia coli using SFP3 as substrate measured a...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502268(CHEMBL4447813)

IC50: 48nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) defatty-acylase activity expressed in Escherichia coli using S...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502269(CHEMBL4446458)

IC50: 50nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) demyristoylase activity expressed in Escherichia coli using p5...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502268(CHEMBL4447813)

IC50: 51nMAssay Description:Inhibition of recombinant human SIRT2 demyristoylase activity using p53(Myr)-AMC as substrate measured after 3 hrs in presence of NAD+ and trypsin by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502269(CHEMBL4446458)

IC50: 55nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) defatty-acylase activity expressed in Escherichia coli using SFP3 as substrate measured a...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502281(CHEMBL4529328)

IC50: 63nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502270(CHEMBL4458848)

IC50: 67nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502265(CHEMBL4461872)

IC50: 68nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502268(CHEMBL4447813)

IC50: 71nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) demyristoylase activity expressed in Escherichia coli using p5...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502268(CHEMBL4447813)

IC50: 77nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) defatty-acylase activity expressed in Escherichia coli using SFP3 as substrate measured a...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502281(CHEMBL4529328)

IC50: 84nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) demyristoylase activity expressed in Escherichia coli using p5...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502267(CHEMBL4457496)

IC50: 98nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) demyristoylase activity expressed in Escherichia coli using p5...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502281(CHEMBL4529328)

IC50: 110nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502278(CHEMBL4438193)

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502269(CHEMBL4446458)

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502267(CHEMBL4457496)

IC50: 110nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) defatty-acylase activity expressed in Escherichia coli using SFP3 as substrate measured a...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502266(CHEMBL4553811)

IC50: 120nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502269(CHEMBL4446458)

IC50: 120nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) defatty-acylase activity expressed in Escherichia coli using S...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502266(CHEMBL4553811)

IC50: 120nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502278(CHEMBL4438193)

IC50: 130nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) demyristoylase activity expressed in Escherichia coli using p53(Myr)-AMC as substrate mea...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502267(CHEMBL4457496)

IC50: 130nMAssay Description:Inhibition of recombinant human SIRT2 demyristoylase activity using p53(Myr)-AMC as substrate measured after 3 hrs in presence of NAD+ and trypsin by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50276140(CHEMBL4129995)

IC50: 140nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50148781(CHEMBL3770903)

IC50: 140nMAssay Description:Inhibition of SIRT2 deacylation activity (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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3D Structure (crystal)

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502265(CHEMBL4461872)

IC50: 140nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) demyristoylase activity expressed in Escherichia coli using p5...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502267(CHEMBL4457496)

IC50: 170nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502265(CHEMBL4461872)

IC50: 180nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) defatty-acylase activity expressed in Escherichia coli using SFP3 as substrate measured a...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502268(CHEMBL4447813)

IC50: 180nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502269(CHEMBL4446458)

IC50: 190nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) demyristoylase activity expressed in Escherichia coli using p53(Myr)-AMC as substrate mea...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502280(CHEMBL4457681)

IC50: 190nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502272(CHEMBL4465910)

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502265(CHEMBL4461872)

IC50: 190nMAssay Description:Inhibition of recombinant human SIRT2 demyristoylase activity using p53(Myr)-AMC as substrate measured after 3 hrs in presence of NAD+ and trypsin by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502278(CHEMBL4438193)

IC50: 250nMAssay Description:Inhibition of recombinant human N-terminal polyhis-tagged SIRT6 (1 to 355 residues) defatty-acylase activity expressed in Escherichia coli using SFP3...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502281(CHEMBL4529328)

IC50: 250nMAssay Description:Inhibition of recombinant human SIRT2 demyristoylase activity using p53(Myr)-AMC as substrate measured after 3 hrs in presence of NAD+ and trypsin by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502265(CHEMBL4461872)

IC50: 260nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502281(CHEMBL4529328)

IC50: 270nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) defatty-acylase activity expressed in Escherichia coli using S...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502276(CHEMBL4449389)

IC50: 300nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

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NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502270(CHEMBL4458848)

IC50: 320nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502278(CHEMBL4438193)

IC50: 330nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) defatty-acylase activity expressed in Escherichia coli using S...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502267(CHEMBL4457496)

IC50: 330nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) demyristoylase activity expressed in Escherichia coli using p53(Myr)-AMC as substrate mea...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502268(CHEMBL4447813)

IC50: 340nMAssay Description:Inhibition of recombinant human SIRT3 (118 to 399 residues) demyristoylase activity expressed in Escherichia coli using p53(Myr)-AMC as substrate mea...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502267(CHEMBL4457496)

IC50: 400nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged SIRT1 (Met1 to Ser747 residues) defatty-acylase activity expressed in Escherichia coli using S...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

NAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL

BDBM50502273(CHEMBL4464941)

IC50: 400nMAssay Description:Inhibition of recombinant human SIRT2 deacylation activity using Fluor de Lys Sirt2 as substrate measured at 5 mins interval for 30 mins in presence ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

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