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Found 4 Enz. Inhib. hit(s) with all data for entry = 50007516
TargetBeta-secretase 1(Homo sapiens (Human))
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)
Affinity DataIC50:  15nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK-Quencher substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50510073(CHEMBL4443976)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK-Quencher substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50510075(CHEMBL4576721)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK-Quencher substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50510074(CHEMBL4533100)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK-Quencher substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed