Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50008187
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516619(CHEMBL4547542)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of human recombinant BRAF V600E mutant using MEK1 as substrate measured after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50484216(CHEMBL1822256)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant BRAF V600E mutant using MEK1 as substrate measured after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516609(CHEMBL4445595)
Affinity DataIC50:  32nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516607(CHEMBL4530882)
Affinity DataIC50:  92nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516620(CHEMBL4557039)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516612(CHEMBL4527473)
Affinity DataIC50:  157nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516611(CHEMBL4586188)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516608(CHEMBL4539692)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516618(CHEMBL4546383)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516613(CHEMBL4441288)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516605(CHEMBL4519570)
Affinity DataIC50:  470nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516615(CHEMBL4571674)
Affinity DataIC50:  540nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516617(CHEMBL4448871)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516606(CHEMBL4470156)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516616(CHEMBL4588836)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516610(CHEMBL4435526)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50516614(CHEMBL4459079)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human recombinant N-terminal GST/His6-tagged BRAF V600E mutant (Q417 to H766 residues) expressed in Sf9 insect cells using MEK1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed