Found 14 Enz. Inhib. hit(s) with all data for entry = 50008754 TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of cMET (unknown origin) using FAM-labeled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift...More data for this Ligand-Target Pair
3D Structure (crystal)TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of cMET (unknown origin) using FAM-labeled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 20 mins by color...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of PLK1 PBD (unknown origin) using GPMQSpTPLNG-OH as fluorescent probe incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DHODH (31 to 395 residues) expressed in Escherichia coli using dihydroorotate substrate preincu...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of PLK1 PBD (unknown origin) using GPMQSpTPLNG-OH as fluorescent probe incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-D-glucopyranoside as substrate pre-incubated for 15 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of 5-lipoxygenase (unknown origin) incubated for 10 minsMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production by Berthelot colorimetric methodMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of 5-lipoxygenase (unknown origin) incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Affinity DataIC50: 6.86E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 3 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
