Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50006693
TargetCytochrome P450 1A2(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 10 mins followed by substrate addition further incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 10 mins followed by substrate addition further incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by whole-cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataIC50: >5.00E+4nMAssay Description:Binding affinity to human recombinant GST-tagged FXR LBD (193-472 residues) expressed in baculovirus infected insect cells incubated for 1 hr by lumi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 10 mins followed by substrate addition further incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 10 mins followed by substrate addition further incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate incubated for 10 mins followed by substrate addition further incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502543(CHEMBL4436335)
Affinity DataEC50:  27nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataEC50:  8nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502541(Elafibranor | GFT-505 | Gft505)
Affinity DataEC50:  225nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502541(Elafibranor | GFT-505 | Gft505)
Affinity DataEC50:  115nMAssay Description:Agonist activity at PPARbeta (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502543(CHEMBL4436335)
Affinity DataEC50:  457nMAssay Description:Agonist activity at PPARgamma (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502543(CHEMBL4436335)
Affinity DataEC50:  5nMAssay Description:Agonist activity at PPARbeta (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502544(CHEMBL4566817)
Affinity DataEC50:  2.82E+3nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50099491(2-(4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502545(CHEMBL4460024)
Affinity DataEC50:  3.42E+3nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502542(CHEMBL4483327)
Affinity DataEC50:  8.97E+3nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50085041(2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at PPARbeta (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataEC50:  5nMAssay Description:Agonist activity at PPARbeta (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502541(Elafibranor | GFT-505 | Gft505)
Affinity DataEC50:  2.12E+3nMAssay Description:Agonist activity at PPARgamma (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502539(CHEMBL4470753)
Affinity DataEC50:  2.94E+3nMAssay Description:Agonist activity at PPARgamma (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502540(CHEMBL4516239)
Affinity DataEC50:  385nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50502546(CHEMBL4587533)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at PPARalpha (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataEC50:  215nMAssay Description:Agonist activity at PPARgamma (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed