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Found 11 Enz. Inhib. hit(s) with all data for entry = 50009273
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50:  12.7nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM50526706(CHEMBL4545676)
Affinity DataIC50:  270nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM192670(3-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-1-(4-o-...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM192678(1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(6-methoxy-...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM192669(3-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-1-(4-ph...)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM50526705(CHEMBL106731)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(CHEBI:76010 | Dolutegravir | GSK1349572 | S-349572)
Affinity DataEC50:  3.60nMAssay Description:Inhibition of HIV-1 NL4-3 integrase E92Q/N155H double mutantMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(CHEBI:76010 | Dolutegravir | GSK1349572 | S-349572)
Affinity DataEC50:  6.80nMAssay Description:Inhibition of HIV-1 NL4-3 integrase G140S/Q148R double mutantMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(CHEBI:76010 | Dolutegravir | GSK1349572 | S-349572)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of HIV-1 NL4-3 integrase T97A/Y143C double mutantMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 2)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(CHEBI:76010 | Dolutegravir | GSK1349572 | S-349572)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of wild type HIV-2 ROD9 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM50062551(CHEBI:76010 | Dolutegravir | GSK1349572 | S-349572)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 integraseMore data for this Ligand-Target Pair