Found 50 Enz. Inhib. hit(s) with all data for entry = 50009444 TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
3D Structure (crystal)TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.59E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 2.22E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
