Found 5 Enz. Inhib. hit(s) with all data for entry = 50007622 TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 0.930nMAssay Description:Inhibition of wild type human N-terminal GST-fusion tagged TRKB kinase domain (456 to 822 residues) expressed in baculovirus expression system by HTR...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of wild type human His-tagged TRKA kinase domain (441 to 796 residues) expressed in baculovirus expression system by HTRF assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of TRKA E735A mutant (unknown origin) expressed in baculovirus infected sf9 cells assessed as kinase domain dimerization by HTRF assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 199nMAssay Description:Inhibition of wild type human His-tagged TRKA kinase domain (441 to 796 residues) expressed in baculovirus expression system by HTRF assayMore data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of wild type human N-terminal GST-fusion tagged TRKB kinase domain (456 to 822 residues) expressed in baculovirus expression system by HTR...More data for this Ligand-Target Pair
